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基于华大智造测序平台已发表的文章

2019-09-29

序号

物种

物种大类

文献名称

期刊

影响因子

年份

测序技术

1

叶甲

动物

Comparative transcriptome analysis of chemosensory genes in two sister leaf beetles provides insights into chemosensory speciation

Insect Biochemistry and Molecular Biology

3.756

2016

RNA-Seq

2

cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs

Clinical Epigenetics

4.987

2016

Small RNA

3

Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype

Oncotarget

5.168

2017

RNA-Seq

4

Overexpression of placenta specific 8 is associated with malignant progression and poor prognosis of clear cell renal cell carcinoma

International Urology and Nephrology

1.564

2017

RNA-Seq

5

水稻

植物

Overexpression of OsHSP18.0-CI Enhances Resistance to Bacterial Leaf Streak in Rice

Rice

3.739

2017

RNA-Seq

6

克雷伯氏菌

细菌

Coordination of metabolic pathways: Enhanced carbon conservation in 1,3-propanediol production by coupling with optically pure lactate biosynthesis

Metabolic Engineering

8.142

2017

RNA-Seq

7

A reference human genome dataset of the BGISEQ-500 sequencer

GigaScience

7.267

2017

WGS

8

大花红景天

植物

Draft genome sequence of the Tibetan medicinal herb, Rhodiola crenulata

GigaScience

7.267

2017

RNA-Seq

9

果蝇

动物

Drug induces depression-like phenotypes and alters gene expression profiles in Drosophila

Brain Research Bulletin

3.033

2017

RNA-Seq

10

狗和狼

动物

Comparative performance of the BGISEQ-500 versus Illumina HiSeq2500 sequencing platforms for palaeogenomic sequencing

GigaScience

7.267

2017

WGS

11

Recessive mutation in EXOSC3 associates with mitochondrial dysfunction and pontocerebellar hypoplasia

Mitochondrion

3.704

2017

RNA-Seq

12

油菜

植物

Genome-scale mRNA transcriptomic insights into the responses of oilseed rape (Brassica napus L.) to varying boron availabilities

Plant and Soil

3.052

2017

RNA-Seq

13

小鼠

动物

Nuclear carbonic anhydrase 6B associates with PRMT5 to epigenetically promote IL-12 expression in innate response

PNAS

9.661

2017

RNA-Seq&ChIP-Seq

14

Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity

Cell

30.41

2017

RNA-Seq

15

拟南芥

植物

AtACS8 plays a critical role in the early biosynthesis of ethylene elicited by copper ions in Arabidopsis

Journal of Cell Science

4.431

2017

RNA-Seq

16

The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer

The Journal of Clinical Investigation

12.784

2017

ChIP-Seq

17

文昌鱼

动物

Transcriptome-wide analysis of immune-responsive microRNAs against poly (I:C) challenge in Branchiostoma belcheri by deep sequencing and bioinformatics

Oncotarget

5.168

2017

Small RNA

18

PBRM1 restricts the basal activity of innate immune system through repressing RIG-I-like receptor signaling and is a potential prognostic biomarker for colon cancer

The Journal of Pathology

6.894

2017

RNA-Seq

19

文昌鱼

动物

Exploring gene expression changes in the amphioxus gill after poly(I:C) challenge using digital expression profiling

Fish & Shellfish Immunology

3.148

2017

RNA-Seq

20

海参

动物

Genome-wide analysis of gene expression profile in the respiratory tree of sea cucumber (Apostichopus japonicus) in response to hypoxia conditions

Journal of the Marine Biological Association of the United Kingdom

1.038

2017

RNA-Seq

21

FH535 Inhibits Proliferation and Motility of Colon Cancer Cells by Targeting Wnt/β-catenin Signaling Pathway

Journal of Cancer

2.916

2017

RNA-Seq

22

小鼠

动物

Data Descriptor: RNA sequencing analysis of activated macrophages treated with the anti-HIV ABX464 in intestinal inflammation

Scientific Data

4.836

2017

RNA-Seq

23

小鼠

动物

Orally Administrated Bakers Yeast beta-Glucan Promotes Glucose and Lipid Homeostasis in the Livers of ob/ob Mice

Journal of Agricultural and Food Chemistry

3.154

2017

RNA-Seq

24

韭菜迟眼蕈蚊

动物

Using Next-Generation Sequencing to Detect Differential Expression Genes in Bradysia odoriphaga after Exposure to Insecticides

International Journal of Molecular Sciences

3.226

2017

RNA-Seq

25

鹿角杯形珊瑚

动物

Systemic response of the stony coral Pocillopora damicornis against acute cadmium stress

Aquatic Toxicology

4.129

2017

RNA-Seq

26

小鼠

动物

Characteristics of NK cells from leukemic microenvironment in MLL-AF9 induced acute myeloid leukemia

Molecular Immunology

3.236

2017

RNA-Seq

27

海参

动物

Differential gene expression in the intestine of sea cucumber (Apostichopus japonicus) under low and high salinity conditions

Comparative Biochemistry and Physiology D-Genomics & Proteomics

2.857

2017

RNA-Seq

28

人细胞系

Dual inhibition of DNMTs and EZH2 can overcome both intrinsic and acquired resistance of myeloma cells to IMiDs in a cereblonindependent manner

Molecular oncology

5.314

2017

RNA-seq

29

人白血病

Heterogeneous effects of M-CSF isoforms on the progression of MLL-AF9 leukemia

Immunology and cell biology

4.557

2017

RNA-seq

30

苎麻

植物

Gene expression profiling of ramie roots during hydroponic induction and adaption to aquatic environment

Genomics Data

2.801

2017

RNA-Seq

31

Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells

Journal of Experimental & Clinical Cancer Research

5.189

2017

RNA-Seq

32

扩展青霉

真菌

Identification of differentially expressed genes involved in spore germination of Penicillium expansum by comparative transcriptome and proteome approaches

MicrobiologyOpen

2.747

2017

RNA-Seq

33

胰管腺癌

High expression of diffuse panbronchiolitis critical region 1 gene promotes cell proliferation, migration and invasion in pancreatic ductal adenocarcinoma

Biochemical and Biophysical Research Communications

2.466

2017

RNA-Seq

34

Probing impaired neurogenesis in human brain organoids exposed to alcohol

Integrative Biology

3.252

2017

RNA-Seq

35

Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing

GigaScience

7.267

2017

metagenome

36

盐生草

植物

Transcriptome sequencing and comparative analysis of differentially-expressed isoforms in the roots of Halogeton glomeratus under salt stress

Gene

2.415

2017

RNA-Seq

37

青鳉鱼

动物

Transcriptomic analysis reveals transgenerational effect of hypoxia on the neural control of testicular functions

Aquatic Toxicology

4.129

2017

RNA-Seq

38

小鼠

动物

Effects of In Utero PFOS Exposure on Transcriptome, Lipidome and Function of Mouse Testis

Environmental Science & Technology

6.198

2017

RNA-Seq

39

Germline and somatic variant identification using BGISEQ-500 and HiSeq X Ten whole genome sequencing

PLOS ONE

3.057

2018

WGS

40

螺和牡蛎

动物

Conserved and ubiquitous expression of piRNAs and PIWI genes in mollusks antedates the origin of somatic PIWI/piRNA expression to the root of bilaterians

bioRxiv

2018

Small RNA

41

拟南芥

植物

Phytochrome A Negatively Regulates the Shade Avoidance Response by Increasing Auxin/Indole Acidic Acid Protein Stability

Developmental Cell

9.174

2018

RNA-Seq

42

西瓜

植物

Comparative transcriptome analysis reveals key genes potentially related to soluble sugar and organic acid accumulation in watermelon

PLOS ONE

3.057

2018

RNA-Seq

43

青蒿

植物

A novel HD-ZIP IV/MIXTA complex promotes glandular trichome initiation and cuticle development in Artemisia annua

New Phytologist

7.33

2018

RNA-Seq

44

A novel mutation in PRPF31, causative of autosomal dominant retinitis pigmentosa, using the BGISEQ-500 sequencer

International journal of ophthalmology

1.1

2018

WES

45

大鼠

动物

Preinduction with bone morphogenetic protein-2 enhances cardiomyogenic differentiation of c-kit+ mesenchymal stem cells and repair of infarcted myocardium

International Journal of Cardiology

6.189

2018

RNA-seq

46

拟南芥

植物

The GARP/MYB-related grape transcription factor AQUILO improves cold tolerance and promotes the accumulation of raffinose family oligosaccharides

Journal of Experimental Botany

5.83

2018

RNA-seq

47

动物

An integrated biomanufacturing platform for the large-scale expansion and neuronal differentiation of human pluripotent stem cell-derived neural progenitor cells"

Acta Biomaterialia

6.319

2018

RNA-seq

48

小鼠

动物

Cambogin suppresses dextran sulphate sodiuminduced colitis by enhancing Treg cell stability and function

British journal of pharmacology

5.49

2018

RNA-seq

49

人细胞系

FBXL10 contributes to the development of diffuse large B-cell lymphoma by epigenetically enhancing ERK1/2 signaling pathway

Cell death & disease

5.965

2018

RNA-seq

50

拟南芥

植物

Arabidopsis thaliana ACS8 plays a crucial role in the early biosynthesis of ethylene elicited by Cu2+ ions

JOURNAL OF CELL SCIENCE

4.431

2018

RNA-seq

51

小鼠

动物

Dual extra-retinal origins of microglia in the model of retinal microglia repopulation

Cell Discovery

2018

RNA-Seq

52

Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through repression of phosphoglycerate dehydrogenase

Theranostics

8.766

2018

RNA-Seq

53

豌豆蚜

动物

A small set of differentially expressed genes was associated with two color morphs in natural populations of the pea aphid Acyrthosiphon pisum

Gene

2.415

2018

RNA-Seq

54

Selenite and methylseleninic acid epigenetically affects distinct gene sets in myeloid leukemia: A genome wide epigenetic analysis

Free Radical Biology and Medicine

5.606

2018

RNA-Seq

55

小鼠

动物

Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion

Nature Neuroscience

17.839

2018

RNA-Seq

56

宏基因组

微生物

A novel affordable reagent for room temperature storage and transport of fecal samples for metagenomic analyses

Microbiome

8.496

2018

metagenome

57

番茄

植物

Transcriptome resequencing analysis of the responses of Ty5-Mediated resistance to TYLCV via in resistant vs. susceptible tomato cultivars

PeerJ

2.17

2018

RNA-seq

58

宏基因组

微生物

Efficacy and safety of faecal microbiota transplantation in patients with psoriatic arthritis: protocol for a 6-month, double-blind, randomised, placebo-controlled trial

BMJ OPEN

2.369

2018

metagenome

59

人细胞系

Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival

Cell death & disease

5.965

2018

RNA-seq

60

小鼠

动物

KRAB-type zinc-finger proteins PITA and PISA specifically regulate p53-dependent glycolysis and mitochondrial respiration

Cell research

15.606

2018

RNA-seq

61

小鼠

动物

The LIS1/NDE1 Complex Is Essential for FGF Signaling by Regulating FGF Receptor Intracellular Trafficking

Cell Reports

8.282

2018

RNA-Seq

62

植物

植物

A guide to sequence your favorite plant genomes

Applications in plant sciences

1.49

2018

Review

63

人胃癌

The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1

Molecular Cancer

6.204

2018

RNA-seq

64

根霉

真菌

Comparative genome-wide analysis of extracellular small RNAs from the mucormycosis pathogen Rhizopus delemar

Scientific Reports

4.259

2018

Small RNA

65

甲状腺癌

TBX3 promotes proliferation of papillary thyroid carcinoma cells through facilitating PRC2-mediated p57KIP2 repression

Oncogene

7.519

2018

RNA-seq

66

胃癌

Silkworm Pupa Protein Hydrolysate Induces Mitochondria-Dependent Apoptosis and S Phase Cell Cycle Arrest in Human Gastric Cancer SGC-7901 Cells

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

3.226

2018

RNA-seq

67

拟南芥

植物

Hydrogen peroxide positively regulates brassinosteroid signaling through oxidation of the BRASSINAZOLE-RESISTANT1 transcription factor

Nature Communications

12.124

2018

RNA-seq

68

人细胞系

Small molecules capable of activating DNA methylationrepressed genes targeted by the p38 mitogen-activated protein kinase pathway

Journal of Biological Chemistry

4.125

2018

RNA-seq

69

小鼠

动物

PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis

Developmental cell

9.174

2018

RNA-seq

70

白血病

Leukemia cell-derived microvesicles induce T cell exhaustion via miRNA delivery

OncoImmunology

7.719

2018

RNA-seq

71

酿酒酵母

真菌

RNA-Seq analysis of global transcriptomic changes suggests a roles for the MAPK pathway and carbon metabolism in cell wall maintenance in a Saccharomyces cerevisiae FKS1 mutant

Biochemical and Biophysical Research Communications

2.466

2018

Transcriptome Sequencing

72

卡瓦胡椒

植物

The biosynthetic origin of psychoactive kavalactones in kava

Nature Plants

13.297

2019

Transcriptome Sequencing

73

李斯特菌

细菌

Identification and Characterization of als Genes Involved in D-Allose Metabolism in Lineage II Strain of Listeria monocytogenes

Frontiers in Microbiology

4.076

2018

RNA-seq

74

Cupriavidus 贪铜菌

细菌

In Situ Lignin Bioconversion Promotes Complete Carbohydrate Conversion of Rice Straw by Cupriavidus basilensis B-8

ACS Sustainable Chemistry & Engineering

5.95

2018

RNA-seq

75

大鼠

动物

Cranial Irradiation Induces Hypothalamic Injury and Late-Onset Metabolic Disturbances in Juvenile Female Rats

DEVELOPMENTAL NEUROSCIENCE

3.03

2018

RNA-seq

76

Anti?fbrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohns Disease

Digestive Diseases and Sciences

2.875

2018

RNA-seq

77

Quality Control of Next-generation Sequencing-based In vitro Diagnostic Test for Onco-relevant Mutations Using Multiplex Reference Materials in Plasma

Journal of Cancer

2.916

2018

Review

78

银屑病

An Interleukin-25-Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin Inflammation

Immunity

22.845

2018

RNA-seq

79

人细胞系

Roles of the CSE1L-mediated nuclear import pathway in epigenetic silencing

PNAS

9.661

2018

RNA-seq

80

小麦根际菌

细菌

The Catabolite Repressor/Activator Cra Is a Bridge Connecting Carbon Metabolism and Host Colonization in the Plant Drought Resistance-Promoting Bacterium Pantoea alhagi LTYR-11Z

Applied and Environmental Microbiology

3.807

2018

RNA-seq

81

Efficient and unique co-barcoding of second-generation sequencing reads from long DNA molecules enabling cost effective and accurate sequencing, haplotyping, and de novo assembly

GENOME RESEARCH

11.922

2019

stLFR

82

玉米象虫

动物

Transcriptome profiling reveals differential gene expression of detoxification enzymes in Sitophilus zeamais responding to terpinen-4-ol fumigation

Pesticide Biochemistry and Physiology

2.59

2018

Transcriptome Sequencing

83

Identification of a mutL?homolog 1 mutation via whole?exome sequencing in a Chinese family with Gardner syndrome

Molecular Medicine Reports

1.692

2018

WES

84

大肠杆菌

细菌

Differential gene expression in Escherichia coli during aerosolization from liquid suspension

Applied Microbiology and Biotechnology

3.42

2018

RNA-seq

85

大鼠肠道

动物

A gene catalogue of the Sprague-Dawley rat gut metagenome

GigaScience

7.267

2018

metagenome

86

龙血树

植物

Complete plastome sequence of Dracaena cambodiana (Asparagaceae): a species considered Vulnerable in Southeast Asia

Mitochondrial DNA Part B

0.488

2018

plastome Sequencing

87

人外泌体

Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy

The American Journal of Human Genetics

9.025

2018

RNA-seq

88

牡蛎

动物

The Molecular Mechanism Underlying Pro-apoptotic Role of Hemocytes Specific Transcriptional Factor Lhx9 in Crassostrea hongkongensis

Frontiers in Physiology

4.134

2018

RNA-seq

89

拟南芥

植物

Overexpression of VaWRKY14 increases drought tolerance in Arabidopsis by modulating the expression of stress-related genes

Plant Cell Reports

2.869

2018

RNA-seq

90

盐芥

植物

Compositional and transcriptomic analysis associated with cuticle lipid production on rosette and inflorescence stem leaves in the extremophyte Thellungiella salsuginea

physiologia plantarum

3.3

2018

RNA-seq

91

酵母

真菌

Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods

Nature Communications

12.124

2018

WGS

92

小鼠

动物

Global expression profiling and pathway analysis of mouse mammary tumor reveals strain and stage specific dysregulated pathways in breast cancer progression

Cell Cycle

3.53

2018

RNA-seq

93

STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection

Nature Communications

12.124

2018

RNA-seq

94

水稻

植物

DDM1 represses noncoding RNA expression and RNA-directed DNA methylation in heterochromatin

Plant Physiology

6.456

2018

Small RNA

95

恒河猴

动物

Genetic screening and multipotency in rhesus monkey haploid neural progenitor cells

Development

5.843

2018

RNA-seq

96

人唇裂

A novel PTCH1 mutation underlies nonsyndromic cleft lip and/or palate in a Han Chinese family

oral diseases

2.01

2018

WES

97

白背飞虱

动物

Comparative transcriptome analysis of Sogatella furcifera (Horváth) exposed to different insecticides

Scientific Reports

4.259

2018

Transcriptome Sequencing

98

感染性心内膜炎

Identification of pathogens in culture-negative infective endocarditis with metagenomic analysis

Annals of Clinical Microbiology and Antimicrobials

3.155

2018

metagenome

99

Reliable Multiplex Sequencing with Rare Index Mis-Assignment on DNB-Based NGS Platform

BMC Genomics

3.73

2018

WGS&PCR-Free

100

人细胞系

Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy

Journal of Pharmacology and Experimental Therapeutics

3.867

2018

RNA-seq&Small RNA

101

半滑舌鳎

动物

Transcriptome profiling of immune-responsive genes in the intestine of Cynoglossus semilaevis Günther challenged with Shewanella algae

Fish & Shellfish Immunology

3.148

2018

RNA-seq

102

番茄

植物

Expression of grape ACS1 in tomato decreases ethylene and alters the balance between auxin and ethylene during shoot and root formation

Journal of Plant Physiology

3.121

2018

RNA-seq

103

卵巢癌

C/EBPβ enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylation

Nature Communications

12.124

2018

WES

104

分枝杆菌

细菌

Diagnosis of local hepatic tuberculosis through next-generation sequencing: Smarter, faster and better

Clinics and Research in Hepatology and Gastroenterology

2.623

2018

Pathogen detection

105

黄瓜

植物

Differential Gene Expression Caused by the F and M Loci Provides Insight Into Ethylene-Mediated Female Flower Differentiation in Cucumber

Front. Plant Sci.

3.678

2018

RNA-seq

106

自发性早产

Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth

PLOS.Genetics

5.54

2018

WES

107

寄生蜂

动物

Parasitic insect-derived miRNAs modulate host development

Nature Communications

12.124

2018

Small RNA

108

The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer.

J Pathol

6.253

2018

RNA-seq

109

人细胞系

Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth

Nature Communications

12.124

2018

RNA-Seq

110

人间质细胞

Differential and Interactive Effects of Substrate Topography and Chemistry on Human Mesenchymal Stem Cell Gene Expression

International Journal of Molecular Sciences.

3.687

2018

RNA-Seq

111

拟南芥

植物

Comparative performance of the BGISEQ-500 and Illumina HiSeq4000 sequencing platforms for transcriptome analysis in plants

Plant Methods

4.269

2018

RNA-seq

112

水稻

植物

Modulating plant growthmetabolism coordination for sustainable agriculture

Nature

41.577

2018

RNA-Seq&ChIP-Seq

113

小鼠

动物

Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation

Neuron

14.318

2018

RNA-Seq

114

3 Branch ligation: a novel method to ligate non-complementary DNA to recessed or internal 30OH ends in DNA or RNA

DNA RES

5.404

2018

stLFR

115

Validation of combinatorial probeanchor ligation-based sequencing as non-invasive prenatal test for trisomy at a central laboratory

Ultrasound in Obstetrics & Gynecology

4.71

2017

NIFTY

116

植物

植物

10KP: A Phylodiverse Genome Sequencing Plan

GigaScience

7.267

2018

COMMENTARY

117

动物

Chromosome-level reference genome of the Siamese fighting fish Betta splendens, a model species for the study of aggression

GigaScience

7.267

2018

Hi-C library

118

番茄

植物

Comparative Transcriptome Profiling of Two Tomato Genotypes in Response to Potassium-Deficiency Stress

International Journal of Molecular Sciences

3.687

2018

RNA-Seq

119

The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function

PLOS ONE

3.057

2018

Small RNA

120

The metagenome of the female upper reproductive tract

GigaScience

7.267

2018

metagenome

121

病毒

基于宏基因二代测序技术检测呼吸道病毒的临床应用

中华医院感染学杂志

2018

metagenome

122

苜蓿

植物

Multiple Regulatory Networks Are Activated during Cold Stress in Medicago sativa L

International Journal of Molecular Sciences

3.687

2018

RNA-Seq

123

大鼠

动物

Hippocampal gene expression profiling in a rat model of functional constipation reveals abnormal expression genes associated with cognitive function

Neuroscience Letters

2.18

2018

RNA-Seq

124

Advanced Whole-Genome Sequencing and Analysis of Fetal Genomes from Amniotic Fluid

Clinical Chemistry

8.636

2018

PGS

125

Isolation and whole genome sequencing of fetal cells from maternal blood towards the ultimate noninvasive prenatal testing

PRENATAL DIAGNOSIS

2.523

2017

PGS

126

Multiplex Cell-Free DNA Reference Materials for Quality Control of Next-Generation Sequencing-Based In Vitro Diagnostic Tests of Colorectal Cancer Tolerance

Journal of Cancer

2.916

2018

cfDNA

127

小鼠

动物

Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis

Annals of the Rheumatic Diseases

12.38

2018

RNA-Seq

128

人细胞系

The epigenetic modifer PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer

Journal of Pathology

6.253

2018

RNA-Seq

129

小鼠

动物

Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in mice

Carbohydrate Polymers

5.158

2018

RNA-Seq

130

斑马鱼

动物

Transcriptome analysis reveals functional roles of nacreous protein N16 in prednisolone-induced osteoporotic zebrafish

International Journal of Biological Macromolecules

3.909

2018

RNA-Seq

131

花生

植物

Comparative transcriptome analysis revealed key factors for differential cadmium transport and retention in roots of two contrasting peanut cultivars

BMC genomics

3.73

2018

RNA-Seq

132

紫花苜蓿

植物

Comparative Transcriptomic and Physiological Analyses of Medicago sativa L. Indicates that Multiple Regulatory Networks Are Activated during Continuous ABA Treatment

Int J Mol Sci.

3.687

2018

RNA-Seq

133

牡蛎

动物

Analysis of in situ Transcriptomes Reveals Divergent Adaptive Response to Hyper- and Hypo-Salinity in the Hong Kong Oyster, Crassostrea hongkongensis

Front. Physiol

3.394

2018

RNA-Seq

134

黄野螟

动物

Candidate olfactory genes identified in Heortia vitessoides(Lepidoptera: Crambidae) by antennal transcriptome analysis

Comparative Biochemistry and Physiology Part D: Genomics and Proteomics

2.913

2018

Transcriptome Sequencing

135

大麦

植物

Transcriptomic comparison of two barley genotypes differing in arsenic tolerance exposed to arsenate and phosphate treatments

Plant Physiology and Biochemistry

2.718

2018

RNA-Seq

136

猪肺泡巨噬细胞

动物

Transcriptome of porcine alveolar macrophages activated by interferon-gamma and lipopolysaccharide

Biochemical and Biophysical Research Communications

2.559

2018

RNA-Seq

137

盐生草

植物

Comparative transcriptome analysis of genes involved in Na+ transport in the leaves of halophyte Halogeton glomeratus

Gene

2.498

2018

RNA-seq

138

动物

RNA-Seq analysis of duck embryo fibroblast cell gene expression during the early stage of egg drop syndrome virus infection

Poultry Science

2.216

2018

RNA-Seq

139

黄野螟

动物

De novo assembly and identification of antennal transcriptome reveals an olfactory system in Heortia vitessoides (Lepidoptera: Crambidae)

PeerJ

2.17

2017

Transcriptome Sequencing

140

植物

Combination of iTRAQ proteomics and RNA-seq transcriptomics reveals jasmonate-related-metabolisms central regulation during the process of Jujube witches broom recovery by tetracycline treatment

Scientia Horticulturae

1.76

2018

RNA-seq

141

The application of NIPT using combinatorial probe-anchor synthesis to identify sex chromosomal aneuploidies (SCAs) in a cohort of 570 pregnancies.

Mol Cytogenet.

1.167

2018

NIFTY

142

细胞系

A new massively parallel nanoball sequencing platform for whole exome research

BMC Bioinformatics

2.448

2019

WES

143

老鼠胚胎
干细胞和人类K562细胞

动物

Comparative analysis of sequencing technologies platforms for single-cell transcriptomics

GENOME BIOLOGY

13.214

2019

scRNA-Seq

144

紫甘蓝、芥蓝

植物

Maintenance of grafting-induced epigenetic variations in the asexual progeny of Brassica oleracea and B juncea chimera

Plant J

5.97

2018

Small RNA

145

外泌体

Exosomes derived from preadipocytes improve osteogenic differentiation, potentially via reduced miR?223 expression

Molecular Medicine Reports

1.692

2018

RNA-Seq

146

秀丽隐杆线虫

动物

A Persistence Detector for Metabolic Network Rewiring in an Animal

CELL REP

8.282

2019

RNA-Seq

147

An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos

Nature Communications

12.124

2019

ATAC-seq&LiCAT-seq

148

革兰氏阳性细菌

细菌

Functional analysis of Leifsonia xyli subsp xyli membrane protein gene Lxx18460 (anti-sigma K)

BMC Microbiol

2.644

2019

RNA-Seq

149


南蛇藤

植物

De novo leaf and root transcriptome analysis to explore biosynthetic pathway of Celangulin V in Celastrus angulatus maxim

BMC GENOMICS

3.729

2019

RNA-Seq

150

Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity

Nature Communications

12.124

2019

scCAT-seq

151

线虫

细菌

The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans

PLOS GENET

6.1

2019

RNA-Seq&ChIP-seq

152

小鼠

动物

Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue

PLOS BIOL

9.797

2019

RNA-Seq

153

水稻

植物

The basic helixloophelix transcription factor, OsPIL15, regulates grain size via directly targeting a purine permease gene OsPUP7 in rice

PLANT BIOTECHNOL J

7.443

2019

RNA-Seq

154

芸苔

植物

Chromosome level comparative analysis of Brassica genomes

PLANT MOL BIOL

3.356

2019

Hi-C library

155

CINP is a novel cofactor of KLF5 required for its role in the promotion of cell proliferation, survival and tumor growth

INT J CANCER

6.513

2019

RNA-Seq

156

Knockdown of KDM2A inhibits proliferation associated with TGF-β expression in HEK293T cell

MOL CELL BIOL

4.398

2019

RNA-Seq

157

Toxoplasma gondii ROP17 inhibits the innate immune response of HEK293T cells to promote its survival

PARASITOL RES

2.329

2019

RNA-Seq

158

番茄

植物

Overexpression of the KNOX gene Tkn4 affects pollen development and confers sensitivity to gibberellin and auxin in tomato

J PLANT BIOL

1.437

2019

RNA-Seq

159

番茄

植物

A tomato Bbox protein SlBBX20 modulates carotenoid biosynthesis by directly activating PHYTOENE SYNTHASE 1, and is targeted for 26S proteasomemediated degradation

New Phytologist

7.33

2019

RNA-Seq

160

Frequency of mutations in 21 hereditary breast and ovarian cancer susceptibility genes among high-risk Chinese individuals

bioRxiv

2019

capture

161

水稻

植物

Expression of Maize MADS Transcription Factor ZmES22 Negatively Modulates Starch Accumulation in Rice Endosperm

INT J MOL SCI

3.226

2019

RNA-Seq

162

MicroRNA profiling from dried blood samples

Critical Reviews in Clinical Laboratory Sciences

6.481

2019

Small RNA

163

拟南芥

植物

Functional analysis for domains of maize PPR protein EMP5 in RNA editing and plant development in Arabidopsis

PLANT GROWTH REGUL

2.646

2019

RNA-Seq

164

Human epidermal growth factor receptor 2 amplification as a biomarker for treatment in patients with lymph node?metastatic penoscrotal extramammary Paget's disease

Oncology Letters

1.664

2019

WGS

165

石斑鱼

动物

A chromosome-level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birth

Molecular Ecology Resources

7.059

2019

RNA-Seq&ATAC-seq

166

文昌鱼

动物

Genome-wide transcriptional response of microRNAs to the benzo(a)pyrene stresD168:D178s in amphioxus Branchiostoma belcheri

CHEMOSPHERE

4.208

2019

Small RNA

167

斑马鱼

动物

Microcystin-LR exposure induced nephrotoxicity by triggering apoptosis in female zebrafish

CHEMOSPHERE

4.208

2019

RNA-Seq

168

Genomic sequencing and editing revealed the GRM8 signaling pathway as potential therapeutic targets of squamous cell lung cancer

CANCER LETT

6.375

2019

WGS&WES

169

Nonobese subjects of Bacteroides and Prevotella enterotypes responded differentially to calorie restriction intervention

bioRxiv

2019

metagenome

170

苜蓿

植物

Full-length transcript sequencing and comparative transcriptomic analysis to evaluate the contribution of osmotic and ionic stress components towards salinity tolerance in the roots of cultivated alfalfa (Medicago sativa L)

BMC Plant Biology

3.964

2019

RNA-Seq

171

Genome-wide identification of protein binding sites on RNAs in mammalian cells

Biochemical and Biophysical Research Communications

2.466

2019

RPBS-Cap

172

文昌鱼

动物

Genome-wide gene expression analysis reveals novel insights into the response to nitrite stress in gills of Branchiostoma belcheri

CHEMOSPHERE

4.208

2019

RNA-Seq

173

小鼠

动物

Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation

INT J CANCER

6.513

2018

RNA-Seq

174

病原体

微生物

Pathogens in Patients with Granulomatous lobular mastitis

INT J INFECT DIS

2.532

2019

Pathogen detection

175

The identification of a transthyretin variant p.D38G in a Chinese family with early-onset leptomeningeal amyloidosis

Journal of Neurology

3.783

2019

WES

176

细菌

微生物

MALDI-TOF Characterization of Protein Expression Mutation During Morphological Changes of Bacteria Under the Impact of Antibiotics

ANAL CHEM

6.32

2019

RNA-Seq

177

单纯性疱疹

微生物

Identification of Putative UL54 (ICP27) Transcription Regulatory Sequences Binding to Oct-1, v-Myb, Pax-6 and Hairy in Herpes Simplex Viruses

Journal of Cancer

2.916

2019

Pathogen detection

178

印度尼西亚的热带水果

植物

Datasets for genome assembly of six underutilized Indonesian fruits

Data in Brief

2019

WGS

179

芸苔

植物

The complete plastid genomes of four species from Brassicales

MITOCHONDR DNA part B

0.488

2019

plastome Sequencing

180

昆虫

动物

Candidate olfactory genes identified in Heortia vitessoides (Lepidoptera: Crambidae) by antennal transcriptome analysis

Comparative Biochemistry and Physiology Part D: Genomics and Proteomics

2.857

2019

RNA-seq

181

病毒

微生物

Genome comparison of African swine fever virus China/2018/AnhuiXCGQ strain and related European p72 Genotype II strains

TRANSBOUND EMERG DIS

3.585

2019

Pathogen detection

182

海稚虫科

动物

Complete mitogenome of a Baltic Sea specimen of the non-indigenous polychaete Marenzelleria neglecta

MITOCHONDR DNA part B

0.488

2019

WGS

183

宏基因组

微生物

Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report

journal of Bone and Joint Infection

2019

Pathogen detection

184

白鲸

动物

The first chromosomelevel genome for a marine mammal as a resource to study ecology and evolution

Molecular Ecology Resources

7.332

2019

WGS

185

宏基因组

微生物

The vagino-cervical microbiome as a woman's life history

bioRxiv

2019

metagenome

186

斑马鱼的近亲Danionella translucida

动物

Hybrid genome assembly and annotation of Danionella translucida

bioRxiv

2019

Transcriptome Sequencing

187

玉米

植物

Molecular Mechanisms Underlying Increase in Lysine Content of Waxy Maize through the Introgression of the opaque2 Allele

INT J MOL SCI

3.226

2019

RNA-Seq

188

企鹅

动物

Mitogenomes uncover extinct penguin taxa and reveal island formation as a key driver of speciation

Molecular Biology and Evolution

6.202

2019

WGS

189

宏基因组

微生物

The biodiversity Composition of Microbiome in Ovarian Carcinoma Patients

Scientific Reports

4.259

2019

RNA-Seq

190

苹果

植物

Methylome and transcriptome analyses of apple fruit somatic mutations reveal the difference of red phenotype

BMC genomics

3.73

2019

RNA-Seq

191

番茄

植物

SlMYB75, an MYB-type transcription factor,promotes anthocyanin accumulation and enhances volatile aroma production in tomato fruits

Horticulture Research

3.6

2019

RNA-Seq

192

小鼠

动物

The effects of perfluorooctanoate on high fat diet induced non-alcoholic fatty liver disease in mice

Toxicology

3.582

2019

RNA-Seq

193

植物

Molecular digitization of a botanical garden: high-depth whole genome sequencing of 689 vascular plant species from the Ruili Botanical Garden

GigaScience

7.267

2019

WGS

194

西洋参

植物

Characterization of the complete chloroplast genome of American ginseng, Panax quinquefolius L.

Mitochondrial DNA Part B

0.488

2019

chloroplast Sequencing

195

楠木

植物

Characterization of the complete chloroplast genome of the Phoebe zhennan S. Lee

Mitochondrial DNA Part B

0.488

2019

chloroplast Sequencing

196

茄子

植物

Comparative transcriptome analysis reveals K+ transporter gene contributing to salt tolerance in eggplant

BMC Plant Biology

3.964

2019

RNA-Seq

197

小鼠

动物

Eradication of glioblastoma by immuno-virotherapy with a retargeted oncolytic HSV in a preclinical model

Oncogene

7.519

2019

RNA-Seq

198

迟眼蕈蚊

动物

Genome-wide analysis of developmental stage-specific transcriptome in Bradysia odoriphaga

Comparative Biochemistry and Physiology D-Genomics & Proteomics

2.857

2019

RNA-Seq

199

A Novel Heterozygous Mutation of the COL4A3 Gene Causes a Peculiar Phenotype without Hematuria and Renal Function Impairment in a Chinese Family

DISEASE MARKERS

2.348

2019

WES

200

Comparative performance of the BGI and Illumina sequencing technology for single-cell RNA sequencing

bioRxiv

2019

scRNA-Seq

201

大鼠

动物

Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro

Aging

5.179

2019

RNA-Seq

202

乳酸杆菌

微生物

Two Strains of Lactobacilli Effectively Decrease the Colonization of VRE in a Mouse Model

Frontiers in cellular and Infection Microbiology

3.52

2019

RNA-Seq

203

动物

Ancient RNA from Late Pleistocene permafrost and historical canids shows tissue-specific transcriptome survival

bioRxiv

2019

RNA-Seq

204

Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells

Nucleic Acids Research

10.162

2019

RNA-Seq

205

Specific Decrease in B-Cell-Derived Extracellular Vesicles Enhances Post-Chemotherapeutic CD8+ T Cell Responses

Immunity

22.845

2019

RNA-Seq

206

小鼠

动物

Ex Vivo Hepatocyte Reprograming Promotes HomologyDirected DNA Repair to Correct Metabolic Disease in Mice After Transplantation

hepatology communications

2019

RNA-Seq

207

啮齿动物

动物

Hepatic IRF6 alleviates liver steatosis and metabolic disorder by transcriptionally suppressing PPARγ

hepatology

13.246

2019

RNA-Seq&ChIP-Seq

208

淋病奈瑟氏球菌

微生物

Identification and expression analysis of ceftriaxone resistance-related genes in Neisseria gonorrhoeae integrating RNA-Seq data and qRT-PCR validation

Journal of Global Antimicrobial Resistance

1.276

2019

RNA-Seq

209

Identification of a Heterozygous Mutation in the TGFBI Gene in a Hui-Chinese Family with Corneal Dystrophy

Journal of Ophthalmology

1.712

2019

RNA-Seq

210

水稻

植物

OsHLH61-OsbHLH96 influences rice defense to brown planthopper through regulating the pathogen-related genes

rice

3.739

2019

RNA-Seq

211

拟南芥

植物

The R2R3-MYB transcription factor MYB49 regulates cadmium accumulation

Plant physiology

6.456

2019

RNA-Seq

212

油菜

植物

Transcriptome analysis of the irregular shape of shoot apical meristem in dt (dou tou) mutant of Brassica napus L.

Molecular Breeding

2.465

2019

RNA-Seq

213

马铃薯

植物

Sequencing and characterization the complete chloroplast genome of the potato, Solanum tuberosum L.

MITOCHONDR DNA part B

0.488

2019

chloroplast Sequencing

214

Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome

Nature Communications

12.124

2019

RNA-Seq

215

小鼠

动物

Transcriptome Profile in Hippocampus During Acute Inflammatory Response to Surgery: Toward Early Stage of PND

Frontiers in Immunology

6.429

2019

RNA-Seq

216

蒲公英

植物

Dandelion polysaccharides exert anticancer effect on Hepatocellular carcinoma by inhibiting PI3K/AKT/mTOR pathway and enhancing immune response

Journal of Functional Foods

3.144

2019

RNA-Seq

217

桃树

植物

A single nucleotide mutation in GID1c disrupts its interaction with DELLA1 and causes a GAinsensitive dwarf phenotype in peach

PLANT BIOTECHNOLOGY JOURNAL

7.443

2019

RNA-Seq

218

裸鼠

动物

RREB1-induced upregulation of the lncRNA AGAP2-AS1 regulates the proliferation and migration of pancreatic cancer partly through suppressing ANKRD1 and ANGPTL4

Cell Death & Disease

5.965

2019

RNA-Seq

219

CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis

Immunity

22.845

2019

RNA-Seq

220

小鼠

动物

Intestinal transcriptional profling reveals fava bean-induced immune response in DBA/1 mice

Biological Research

1.692

2019

RNA-Seq

221

鲈鱼

动物

Transcriptomic analysis of Anabas testudineus and its defensive mechanisms in response to persistent organic pollutants exposure

SCIENCE OF THE TOTAL ENVIRONMENT

4.9

2019

RNA-Seq

222

牦牛

动物

Nutritional Interventions Improved Rumen Functions and Promoted Compensatory Growth of Growth-Retarded Yaks as Revealed by Integrated Transcripts and Microbiome Analyses

Frontiers in microbiology

4.076

2019

RNA-Seq

223

The proinflammatory cytokine TNF-α induces DNA demethylationdependent and independent activation of interleukin-32 expression

Journal of Biological Chemistry

4.125

2019

RNA-Seq

224

硅藻

植物

Complete chloroplast genome of the diatom Skeletonema pseudocostatum from the Western Mediterranean coast of Algeria

MITOCHONDR DNA part B

0.488

2019

chloroplast Sequencing

225

COL1A2 p.Gly1066Val variant identified in a Han Chinese family with osteogenesis imperfecta type I

molecular genetics&genomics

2.979

2019

WES

226

Establishment of a human embryonic stem cell-based liver differentiation model for hepatotoxicity evaluations

Ecotoxicology and Environmental Safety

3.743

2019

RNA-Seq

227

动物

Germline deletion of Cdyl causes teratozoospermia and progressive infertility in male mice

Cell Death & Disease

5.965

2019

RNA-seq

228

Novel GLI3 mutations in Chinese patients with non-syndromic post-axial polydactyly

CURRENT MOLECULAR MEDICINE

2.345

2019

WES

229

马蹄

植物

RNA-Seq analysis of gene expression during the yellowing developmental process of fresh-cut Chinese water chestnuts

Scientia Horticulturae

1.624

2019

RNA-seq

230

动物

Hypoxia causes transgenerational impairment of ovarian development and hatching success in fish

ENVIRONMENTAL SCIENCE & TECHNOLOGY

6.198

2019

RNA-seq

231

Integrated lipidomics and transcriptomics characterization upon aging related changes of lipid species and pathways in human bone marrow mesenchymal stem cells

JOURNAL OF PROTEOME RESEARCH

4.268

2019

RNA-seq

232

动物

Toxicity Induced by Zirconia Oxide Nanoparticles on Various Organs After Intravenous Administration in Rats

Journal of Biomedical Nanotechnology

4.521

2019

RNA-seq

233

Comparative analysis of novel MGISEQ-2000 sequencing platform vs Illumina HiSeq 2500 for whole-genome sequencing

bioRxiv

2019

WGS

234

Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination

Neuron

14.318

2019

RNA-seq

235

Generation of Highly Biomimetic Quality Control Materials for Noninvasive Prenatal Testing Based on Enzymatic Digestion of Matched MotherChild Cell Lines

CLINICAL CHEMISTRY

8.008

2019

NIFTY

236

丹参

植物

Comparative transcriptomic analysis provides insights into the development of a Salvia splendens Ker-Gawler mutant, SX919M

PLoS One

2.806

2019

RNA-seq

237

动物

Absence of GdX/UBL4A Protects against Inflammatory Diseases by Regulating NF-кB Signaling in Macrophages and Dendritic Cells

Theranostics

8.712

2019

RNA-seq

238

动物

Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT

Molecular Cancer

6.204

2019

RNA-seq

239

微藻

植物

Transcriptomic and lipidomic analysis of an EPA-containing Nannochloropsis sp. PJ12 in response to nitrogen deprivation

Scientific Reports

4.259

2019

RNA-seq

240

Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN

Theranostics

8.712

2019

RNA-seq

241

拟南芥

植物

Comparative physiological and transcriptomic analyses reveal the toxic effects of ZnO nanoparticles on plant growth

ENVIRONMENTAL SCIENCE & TECHNOLOGY

6.198

2019

RNA-seq

242

蜘蛛螨

动物

Identification of Saliva Proteins of the Spider Mite Tetranychus evansi by Transcriptome and LCMS/MS Analyses

PROTEOMICS

4.041

2018

RNA-seq

243

蚊子

动物

Mosquito Small RNA Responses to West Nile and Insect-Specific Virus Infections in Aedes and Culex Mosquito Cells

viruses

3.761

2019

Small RNA

244

玫瑰黄色花叶病毒

微生物

Complete genome sequence of a novel member of the family Potyviridae isolated from Phellodendron amurense Rupr. in Liaoning, China

ARCHIVES OF VIROLOGY

2.058

2019

Small RNA

245

动物

An ATAC-seq atlas of chromatin accessibility in mouse tissues

Scientific Data

5.305

2019

ATAC-seq

246

宏基因组

微生物

Life history recorded in the vagino-cervical microbiome

bioRxiv

2019

metagenome

247

MicroRNA signature of air pollution exposureinduced congenital defects

JOURNAL OF CELLULAR PHYSIOLOGY

4.08

2019

Small RNA

248

Decitabine shows synergistic effects with arsenic trioxide against myelodysplastic syndrome cells via endoplasmic reticulum stress-related apoptosis

Journal of Investigative Medicine

1.943

2019

RNA-seq

249

Panel-based NGS reveals disease-causing mutations in hearing loss patients using BGISEQ-500 platform

MEDICINE

1.803

2019

capture

250

Super-enhancers: novel target for pancreatic ductal adenocarcinoma

oncotarget

5.168

2019

RNA-Seq&ChIP-Seq

251

细菌

微生物

An Osmoregulatory Mechanism Operating through OmpR and LrhA Controls the Motile-Sessile Switch in the Plant Growth-Promoting Bacterium Pantoea alhagi

APPLIED AND ENVIRONMENTAL MICROBIOLOGY

3.807

2019

RNA-Seq

252

动物

Metabolic Profiling of Tumors, Sera, and Skeletal Muscles from an Orthotopic Murine Model of Gastric Cancer Associated-Cachexia

JOURNAL OF PROTEOME RESEARCH

4.268

2019

RNA-Seq

253

人细胞系

Targeting super-enhancer-driven oncogenic transcription by CDK7 inhibition in anaplastic thyroid cancer

THYROID

5.515

2019

RNA-Seq&ChIP-Seq

254

秀丽隐杆线虫

动物

Gene-level quantitative trait mapping in an expanded C. elegans multiparent experimental evolution panel

bioRxiv

2019

WGS

255

番茄

植物

Characterization the complete chloroplast genome of the tomato (Solanum lycopersicum L.) from China

MITOCHONDR DNA part B

0.488

2019

chloroplast Sequencing

256

病原体

微生物

Highthroughput identification and diagnostics of pathogens and pests: Overview and practical recommendations

Molecular Ecology Resources

7.332

2018

Pathogen detection

257

猪蛔虫病毒

微生物

Characterization and epidemiological survey of porcine sapelovirus in China

Veterinary Microbiology

2.628

2019

Pathogen detection

258

肠炎沙门氏菌

微生物

Increased growth rate and amikacin resistance of Salmonella enteritidis after onemonth spaceflight on Chinas Shenzhou11 spacecraft

Microbiologyopen

2.747

2019

Pathogen detection

259

真菌

微生物

Intercellular communication is required for trap formation in the nematode-trapping fungus Duddingtonia flagrans

PLOS.Genetics

5.54

2019

RNA-Seq

260

人细胞系

Next-Generation Sequencing Analysis of mRNA Profile in Cisplatin-Resistant Gastric Cancer Cell Line SGC7901

Med Sci Monit

1.585

2019

RNA-Seq

261

黄萎病菌

微生物

Genomewide Transcriptome Profiles Reveal How Bacillus subtilis Lipopeptides Inhibit Microsclerotia Formation in Verticillium dahliae

MOLECULAR PLANT-MICROBE INTERACTIONS

4.332

2019

RNA-Seq

262

人细胞系

Human UTP14a promotes angiogenesis through upregulating PDGFA expression in colorectal cancer

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

2.466

2019

RNA-Seq

263

绿藻

植物

The Complete Chloroplast Genome of Tetraselmis desikacharyi (Chlorodendrophyceae) and Phylogenetic Analysis

Mitochondrial DNA Part B

0.48

2019

chloroplast Sequencing

264

扁形虫

动物

Complete mitogenome of the giant invasive hammerhead flatworm Bipalium kewense

MITOCHONDR DNA part B

0.488

2019

MtDNA sequencing

265

病毒

微生物

The complete nucleotide sequence and genome organization of a novel virus of the order Tymovirales isolated from Prunus davidiana (Carr.) Franch. in Liaoning, China

Archives of Virology

2.058

2019

Small RNA

266

红曲霉

微生物

A Comprehensive Analysis of the Small GTPases Ypt7 Involved in the Regulation of Fungal Development and Secondary Metabolism in Monascus ruber M7

Frontiers in Microbiology

4.076

2019

RNA-Seq

267

玉米

植物

Maize VIVIPAROUS1 Interacts with ABA INSENSITIVE5 to Regulate GALACTINOL SYNTHASE2 Expression Controlling Seed Raffinose Accumulation

Journal of Agricultural and Food Chemistry

3.154

2019

RNA-Seq

268

人细胞系

Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection

International Journal of Molecular Sciences

3.226

2019

Small RNA

269

人细胞系

MicroRNA profiling of plasma exosomes from patients with ovarian cancer using high?throughput sequencing

Oncology Letters

1.664

2019

Small RNA

270

斑马鱼

动物

Acute exposure to ustiloxin A affects growth and development of early life zebrafish, Danio rerio

Chemosphere

4.208

2019

RNA-Seq

271

小鼠

动物

Identification of key genes, pathways, and miRNA/mRNA regulatory networks of CUMS-induced depression in nucleus accumbens by integrated bioinformatics analysis

Neuropsychiatric Disease and Treatment

2.198

2019

RNA-seq&Small RNA

272

宏基因组

微生物

A multi-omic cohort as a reference point for promoting a healthy human gut microbiome

bioRxiv

2019

metagenome

273

Identifying a BRCA2 c.5722_5723del mutation in a Han-Chinese family with breast cancer

BIOSCIENCE REPORTS

2.906

2019

WES

274

高粱

植物

Characterization of the complete chloroplast genome of the Chinese sorghum, Sorghum bicolor from China

MITOCHONDR DNA part B

0.488

2019

chloroplast Sequencing

275

鲸类

动物

The Marine Mammal Class II Major Histocompatibility Complex Organization

Frontiers in Immunology

6.429

2019

WGS

276

草鱼

动物

Transcriptome analysis of rare minnow (Gobiocypris rarus) infected by the grass carp reovirus

Fish & Shellfish Immunology

3.185

2019

RNA-Seq

277

人细胞系

Irradiation-induced dynamic changes of gene signatures reveal gain of metastatic ability in nasopharyngeal carcinoma

American Journal of Cancer Research

3.998

2019

RNA-Seq

278

软骨鱼

动物

Dynamic chromosome rearrangements of the white-spotted bamboo shark shed light on cartilaginous fish diversification mechanisms

bioRxiv

2019

WGS&Hi-C library&RNA-Seq

279

Novel DPY19L2 variants in globozoospermic patients and the overcoming this male infertility

ASIAN JOURNAL OF ANDROLOGY

3.259

2019

WES

280

小鼠

动物

Pharmacological and transcriptome profiling analyses of Fufang E'jiao Jiang during chemotherapy-induced myelosuppression in mice

Journal of Ethnopharmacology

3.115

2019

RNA-Seq

281

Whole genome sequencing reveals complexity in both HPV sequences present and HPV integrations in HPV-positive oropharyngeal squamous cell carcinomas

BMC Cancer

3.288

2019

WGS

282

动物

Genomic variants identified from whole-genome resequencing of indicine cattle breeds from Pakistan

Plos one

2.766

2019

WGS

283

动物

Integrated mRNA and miRNA expression profile analyses reveal the potential roles of sexbiased miRNAmRNA pairs in gonad tissues of the Chinese concaveeared torrent frog (Odorrana tormota)

JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

2.432

2019

RNA-seq&Small RNA

284

拟南芥

植物

The H3K27me3 demethylase REF6 promotes leaf senescence through directly activating major senescence regulatory and functional genes in Arabidopsis

PLOS.Genetics

5.54

2019

RNA-Seq

285

弹尾目

动物

Developmental Expression and Evolution of Hexamerin and Hemocyanin from Folsomia candida (Collembola)

INSECT MOLECULAR BIOLOGY

2.492

2019

RNA-Seq

286

小鼠

动物

Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism

Cell Reports

8.282

2019

RNA-Seq

287

Frizzled 2induced epithelialmesenchymal transition correlates with vasculogenic mimicry, stemness, and Hippo signaling in hepatocellular carcinoma

cancer science

4.372

2019

RNA-Seq

288

猩红热链球菌

微生物

猩红热链球菌高通量测序基因组DNA提取方法研究

华南预防医学

2019

Pathogen detection

289

蚕豆

植物

Identification and Characterization of Salt-Responsive MicroRNAs in Vicia faba by High-Throughput Sequencing

genes

3.191

2019

Small RNA

290

人细胞系

Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer

Molecular Cancer

7.776

2019

ChIP-seq

291

Single cell RNA sequencing reveals cellular diversity of trisomy 21 retina

bioRxiv

2019

scRNA-Seq

292

Single cell RNA-seq reveals cellular diversity and developmental characteristics of human infant retina

bioRxiv

2019

scRNA-Seq

293

玉米

植物

Transcriptome Dynamics of Double Recessive Mutant, o2o2o16o16, Reveals the Transcriptional Mechanisms in the Increase of Its Lysine and Tryptophan Content in Maize

genes

3.191

2019

RNA-Seq

294

人细胞系

LFMD: a new likelihood-based method to detect low-frequency mutations without molecular tags

bioRxiv

2019

MtDNA sequencing

295

小鼠

动物

YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis

Cell Reports

8.282

2019

RNA-Seq

296

小鼠

动物

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate

CELL RESEARCH

15.393

2019

RNA-Seq

297

斑马鱼

动物

Primary cilia regulate hematopoietic stem and progenitor cell specification through Notch signaling in zebrafish

Nature Communications

12.124

2019

RNA-seq

298

人细胞系

Translation of the circular RNA circβ-catenin promotes liver cancer cell growth through activation of the Wnt pathway

Genome Biology

13.214

2019

RNA-seq

299

帝王蝶

动物

Transcriptomics of monarch butterflies (Danaus plexippus) reveals strong differential gene expression in response to host plant toxicity, but weak response to parasite infection

bioRxiv

2019

RNA-seq

300

宏基因组

微生物

Taxonomic and Functional Characterization of the Microbial Community During Spontaneous in vitro Fermentation of Riesling Must

Frontiers in Microbiology

4.076

2019

metagenome

301

大豆

植物

Integration of metabolome and transcriptome analyses highlights soybean roots responding to phosphorus deficiency by modulating phosphorylated metabolite processes

Plant Physiology and Biochemistry

2.718

2019

RNA-seq

302

人细胞系

ZBTB24 regulates the apoptosis of human T cells via CDCA7/TRAIL-receptor axis

Biochemical and Biophysical Research Communications

2.559

2019

RNA-seq

303

酵母

微生物

High production of fatty alcohols in Yarrowia lipolytica by coordination with glycolysis

Science China Chemistry

2019

RNA-seq

304

人细胞系

A reference system for BRCA mutation detection based on next-generation sequencing in the Chinese population

JOURNAL OF MOLECULAR DIAGNOSTICS

4.88

2019

capture

305

动物

Transcriptomic analysis of small intestinal mucosa from porcine epidemic diarrhea virus infected piglets

Microbial Pathogenesis

2.332

2019

RNA-seq

306

人细胞系

Nobiletin exhibits potent inhibition on tumor necrosis factor alphainduced calcification of human aortic valve interstitial cells via targeting ABCG2 and AKR1B1

Phytotherapy researcch

3.349

2019

RNA-seq

307

人细胞系

Establishment and characterization of a novel childhood acute lymphoblastic leukemia cell line, HXEX-ALL1, with chromosome 9p and 17p deletions

Cancer Cell International

3.96

2019

WGS

308

人细胞系

Nutrient Sensing by the Intestinal Epithelium Orchestrates Mucosal Antimicrobial Defense via Translational Control of Hes1

Cell Host & Microbe

17.872

2019

RNA-seq

309

人细胞系

Genetic Regulation of enoyl-CoA hydratase Domain-Containing 3 in Adipose Tissue Determines Insulin Sensitivity in African Americans and Europeans

DIABETES

7.273

2019

RNA-seq

310

小鼠

动物

Dean flow assisted single cell and bead encapsulation for high performance single cell expression profiling

ACS Sensors

5.711

2019

scRNA-Seq

311

Germline-encoded TCR-MHC contacts promote TCR V gene bias in umbilical cord blood T cell repertoire

bioRxiv

2019

MHC capture

312

木荷

植物

Anticandidal Potential of Stem Bark Extract from Schima superba and the Identification of Its Major Anticandidal Compound

molecule

3.098

2019

RNA-seq

313

小鼠

动物

Rescue of Retinal Degeneration in rd1 Mice by Intravitreally Injected Metformin

frontiers in Molecular Neuroscience

3.902

2019

RNA-seq

314

病原体

微生物

全基因组测序技术在严重脓毒症中的临床价值及集束化护理干预

临床与病理杂志

2019

Pathogen detection

315

病原体

微生物

The application of next-generation sequencing in diagnosing invasive pulmonary aspergillosis:three case reports

American Journal of Translational Research

3.061

2019

Pathogen detection

316

牛疱疹病毒1

微生物

Cellular microRNA bta-miR-2361 inhibits bovine herpesvirus 1 replication by directly targeting EGR1 gene

Veterinary Microbiology

2.524

2019

Pathogen detection

317

斑马鱼

动物

Estrogen accelerates heart regeneration by promoting inflammatory responses in zebrafish

bioRxiv

2019

RNA-seq

318

脐带血细胞

Single-cell transcriptomic landscape of nucleated cells in umbilical cord blood

GigaScience

7.267

2019

scRNA-Seq

319

小鼠

动物

Short-term High Fructose Intake Reprograms the Transcriptional Clock Rhythm of the Murine Extraorbital

Investigative Ophthalmology & Visual Science

3.388

2019

RNA-seq

320

人细胞系

Sequential treatment failures in response to BRAF/MEK and immune checkpoint inhibitors mediated by MAP2K2 and B2M mutations in melanoma

Experimental and Molecular Pathology

2.566

2019

WES

321

人细胞系

Cancerassociated fibroblasts contribute to cisplatin resistance by modulating ANXA3 in lung cancer cells

cancer science

4.372

2019

RNA-seq

322

Genetic and clinical findings in a large cohort of Chinese patients with suspected retinitis pigmentosa

AMERICAN JOURNAL OF OPHTHALMOLOGY

4.795

2019

WES

323

Bismuth drugs tackle Porphyromonas gingivalis and attune cytokine response in human cells

Metallomics

4.069

2019

RNA-seq

324

小鼠

动物

Ferulic acid altered IL-17A/IL-17RA interaction and protected against imiquimod-induced psoriasis-like skin injury in mice

Food and Chemical Toxicology

3.977

2019

RNA-seq

325

小鼠

动物

Alterations in transcriptome and antioxidant activity of naturally aged mice exposed to selenium-rich rice

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

2.8

2019

RNA-seq

326

小鼠

动物

Integrated Omics Reveals Tollip as an Aggravator and Therapeutic Target for Hepatic IschemiaReperfusion Injury in Mice

hepatology

13.246

2019

RNA-seq

327

Screening, prenatal diagnosis, and prenatal decision for sex chromosome aneuploidy

Expert Review of Molecular Diagnostics

3.326

2019

NIFTY

328

Breast milk alkylglycerols sustain beige adipocytes through adipose tissue macrophages

JOURNAL OF CLINICAL INVESTIGATION

13.251

2019

RNA-seq

329

斑马鱼

动物

Loss-of-function of sox3 causes follicle development retardation and reduces fecundity in zebrafish

Protein & Cell

6.228

2019

RNA-seq

330

水稻

植物

A nucleus-localized PPR protein OsNPPR1 is important for mitochondrial function and endosperm development in rice

JOURNAL OF EXPERIMENTAL BOTANY

5.354

2019

RNA-seq

331

棘球绦虫

动物

Long-read sequencing reveals a 4.4 kb tandem repeat region in the mitogenome of Echinococcus granulosus (sensu stricto) genotype G1

Parasites & Vectors

3.163

2019

MtDNA sequencing

332

小鼠

动物

Embryoid body-based RNA-seq analyses reveal a potential TBBPA multifaceted developmental toxicity

Journal of Hazardous Materials

6.434

2019

RNA-seq

333

人细胞系

Glutaminyl cyclase inhibitor contributes to the regulation of HSP70, HSP90, actin, and ribosome on gene and protein levels in vitro

JOURNAL OF CELLULAR BIOCHEMISTRY

2.959

2018

RNA-seq

334

Next-Generation Sequencing and Emerging Technologies

SEMINARS IN THROMBOSIS AND HEMOSTASIS

3.345

2019

review

335

掌叶槭

植物

Comparative transcriptome analysis of genes involved in response to thermal stress and leaf colour change of Acer palmatum

Scientia Horticulturae

1.624

2019

RNA-seq

336

人细胞系

ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development

cell reports

8.282

2019

RNA-seq

337

大鼠

动物

Transcriptome profiling of dorsal root ganglia in a rat model of complex regional pain syndrome type-I reveals potential mechanisms involved in pain

Journal of Pain Research

2.645

2019

RNA-seq

338

螃蟹

动物

Transcriptomic analysis provides insight into the mechanism of salinity adjustment in swimming crab Portunus trituberculatus

Genes & Genomics

0.68

2019

RNA-seq

339

病毒

微生物

Full genome sequence of a novel potexvirus from Euonymus bungeanus Maxim based on RNA-Seq analysis

Archives of Virology

2.16

2019

RNA-seq

340

小鼠

动物

Hepatic Interferon Regulatory Factor 6 Alleviates Liver Steatosis and Metabolic Disorder by Transcriptionally Suppressing Peroxisome ProliferatorActivated Receptor γ in Mice

hepatology

13.246

2019

RNA-seq

341

放线菌

微生物

Aeromicrobium endophyticum sp. nov., an endophytic actinobacterium isolated from reed (Phragmites australis)

Journal of Microbiology

2.319

2019

WGS

342

乳腺癌癌旁组织特异性表达基因分析

遗传

2019

RNA-seq

343

大肠杆菌

微生物

Multifaceted Stoichiometry Control of Bacterial Operons Revealed by Deep Proteome Quantification

frontiers in genetics

4.151

2019

RNA-seq

344

人细胞系

The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control

JOURNAL OF EXPERIMENTAL MEDICINE

10.79

2019

RNA-seq

345

拟南芥

植物

mTERF5 Acts as a Transcriptional Pausing Factor to Positively Regulate Transcription of Chloroplast psbEFLJ

molecular plant

9.326

2019

RNA-seq

346

宏基因组

微生物

Altered respiratory virome and serum cytokine profile associated with recurrent respiratory tract infections in children

Nature Communications

12.124

2019

Pathogen detection

347

SEQdata-BEACON: a comprehensive database of sequencing performance and statistical tools for performance evaluation and yield simulation in BGISEQ-500

bioRxiv

2019

Database&statistical tools

348

人细胞系

Pyroptosis of MCF7 Cells Induced by the Secreted Factors of hUCMSCs

Stem Cells International

3.989

2019

RNA-seq

349

人细胞系

Prospect and challenge of detecting dynamic gene copy number increases in stem cells by whole genome sequencing

Journal of Molecular Medicine

4.938

2019

WGS

350

Germline DNA damage repair gene alterations in Chinese prostate patients: More than HRR and MMR

2019 ASCO Annual Meeting Abstracts

2019

WES

351

A multi-institutional investigation assessing prevalence of germline genetic alterations in Chinese patients with gastric carcinoma

2019 ASCO Annual Meeting Abstracts

2019

capture

352

风轮菜

植物

Transcriptome Analysis of Clinopodium chinense (Benth.) O. Kuntze and Identification of Genes Involved in Triterpenoid Saponin Biosynthesis

International Journal of Molecular Sciences

3.226

2019

RNA-seq

353

小鼠

动物

Transcriptional Profiling of Daily Patterns of mRNA Expression in the C57BL/6J Mouse Cornea

CURRENT EYE RESEARCH

2.12

2019

RNA-seq

354

宏基因组

微生物

Age-dependent sexual dimorphism in the adult human gut microbiota

bioRxiv

2019

metagenome

355

绿藻

植物

Sequencing and comparative analysis of three Chlorella genomes provide insights into strain-specific adaptation to wastewater

bioRxiv

2019

RNA-seq

356

动物

Proteomics and Transcriptomics Analysis Reveals Clues into the Mechanism of the Beneficial Effect of Electrical Stimulation on Rat Denervated Gastrocnemius Muscle

Cellular Physiology and Biochemistry

5.5

2019

RNA-seq

357

Prenatal Diagnosis of Fetuses with Increased Nuchal Translucency by Genome Sequencing Analysis

bioRxiv

2019

CNV-seq

358

人细胞系

c-Jun Overexpressing CAR-T Cells are Exhaustion-Resistant and Mediate Enhanced Antitumor Activity

bioRxiv

2019

RNA-seq

359

动物

Interleukin-17 receptor D constitutes an alternative receptor for interleukin-17A important in psoriasis-like skin inflammation

Science Immunology

2019

RNA-seq

360

动物

Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease

Science Advances

11.511

2019

RNA-Seq&ChIP-Seq

361

动物

The transcription factor Shox2 shapes thalamocortical neuron firing properties by regulation of key ion channels

bioRxiv

2019

RNA-seq

362

拟南芥

植物

Overexpression of AtAGT1 promoted root growth and development during seedling establishment

Plant Cell Reports

2.989

2019

RNA-seq

363

人细胞系

STYK1 promotes tumor growth and metastasis by reducing SPINT2/HAI-2 expression in non-small cell lung cancer

Cell Death & Disease

5.638

2019

RNA-seq

364

A truncating CLDN9 variant is associated with autosomal recessive nonsyndromic hearing loss

Human Genetics

3.93

2019

WGS

365

病原体

微生物

The diagnostic value of metagenomic next-generation sequencing for identifying Streptococcus pneumoniae in paediatric bacterial meningitis

BMC Infectious Diseases

2.62

2019

Pathogen detection

366

苏云金芽孢杆菌

微生物

Transcriptome profiling analysis of the intoxication response in midgut tissue of Agrotis ipsilon larvae to Bacillus thuringiensis Vip3Aa protoxin

Pesticide Biochemistry and Physiology

3.44

2019

RNA-seq

367

Development of coupling controlled polymerizations by adapter-ligation in mate-pair sequencing for detection of various genomic variants in one single assay

DNA RESEARCH

5.415

2019

long mate pair library

368

Actualités du séquen?age dADN-Chroniques génomiques

Med Sci (Paris)

2019

review

369

All Aboard The Genome Exprees: Is a new generation of DNA sequencing technology about to hit the fast track?

Genetic Engineering & Biotechnology New

2019

review

370

Arthropod Genome Sequencing and Assembly Strategies

Insect Genomics

2019

review

371

Clinical metagenomic next-generation sequencing for pathogen detection

Annual Review of Pathology: Mechanisms of Disease

2019

review

372

宏基因组

微生物

Exploring the human microbiome: The potential future role of next-generation sequencing in disease diagnosis and treatment

Frontiers in Immunology

5.511

2019

review

373

鼻咽癌

FOXA1 reprograms the TGF-β-stimulated transcriptional program from a metastasis promoter to a tumor suppressor in nasopharyngeal carcinoma

Cancer letters

6.491

2019

RNA-seq

374

High-throughput sequencing for the aetiologic identification of viral encephalitis, meningoencephalitis and meningitis A narrative review and clinical appraisal

Clinical Microbiology and Infection

5.394

2019

review

375

秀丽隐杆线虫

动物

Systematic evaluation of C elegans lincRNAs with CRISPR knockout mutants

Genome Biology

13.214

2019

lncRNA

376

烟草

植物

Tolerance of Transplastomic Tobacco Plants Overexpressing a Theta Class Glutathione Transferase to Abiotic and Oxidative Stresses

Front. Plant Sci

3.678

2019

RNA-Seq

377

雨生红球藻

植物

Comparative transcriptome analysis of a long-time span two-step culture process reveals a potential mechanism for astaxanthin and biomass hyper-accumulation in Haematococcus pluvialis JNU35

Biotechnol Biofuels

5.497

2019

RNA-Seq&Transcriptome Sequencing

378

小鼠

动物

Identifcation of key genes, pathways, and miRNA/mRNA regulatory networks of CUMS-induced depression in nucleus accumbens by integrated bioinformatics analysis

Neuropsychiatric Disease and Treatment

2.195

2019

RNA-Seq&Small RNA

379

担子菌

微生物

Genomic Evidence of Recombination in the Basidiomycete Wallemia mellicola

genes

3.191

2019

WGS

380

胃癌

LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b

Cancer Cell International

3.96

2019

lncRNA

381

A comprehensive assessment of NextGeneration Sequencing variants validation using a secondary technology

Molecular Genetics & Genomic Medicine

2.695

2019

capture

382

草地贪夜蛾

动物

Chromosome level draft genomes of the fall armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae), an alien invasive pest in China

bioRxiv

2019

stLFR

383

Differential Roles of the mTOR-STAT3 Signaling in Dermal γδ T Cell Effector Function in Skin Inflammation

cell reports

8.032

2019

RNA-seq

384

小鼠

动物

Hyaluronan synthase 2mediated hyaluronan production mediates Notch1 activation and liver fibrosis

Science Translational Medicine

16.71

2019

RNA-seq

385

胃癌

Hydroxychloroquine enhances the antitumor effects of BC001 in gastric cancer

International Journal of Oncology

3.333

2019

RNA-seq

386

水稻

植物

The nuclear-localized PPR protein OsNPPR1 is important for mitochondrial function and endosperm development in rice

Journal of experimental botany

5.354

2019

RNA-seq

387

疱疹病毒

微生物

Differential expression profiling of lncRNAs related to EpsteinBarr virus infection in epithelial cells

JOURNAL OF MEDICAL VIROLOGY

1.988

2019

lncRNA

388

病原体

微生物

Metagenomic Next-generation Sequencing of Cerebrospinal Fluid for the Diagnosis of Central Nervous System Infections: A Multicentre Prospective Study

bioRxiv

2019

Pathogen detection

389

植物

A symbiotic balancing act: arbuscular mycorrhizal specificity and specialist fungus gnat pollination in the mycoheterotrophic genus Thismia (Thismiaceae)

Annals of Botany

3.646

2019

WGS

390

莲花

植物

Transcription Profiles Reveal the Regulatory Synthesis of Phenols during the Development of Lotus Rhizome (Nelumbo nucifera Gaertn)

International Journal of Molecular Sciences

3.687

2019

RNA-seq

391

鲱鱼

动物

A chromosome-level assembly of the Atlantic herring detection of a supergene and other signals of selection

bioRxiv

2019

Hi-C library

392

宏基因组

微生物

Distinct gut metagenomics and metaproteomics signatures in prediabetics and treatment-na?ve type 2 diabetics

bioRxiv

2019

metagenome

393

肺癌

Irradiation increases the immunogenicity of lung cancer cells and irradiation-based tumor cell vaccine elicits tumor-specific T cell responses in vivo

OncoTargets and Therapy

2.656

2019

RNA-seq

394

小鼠

动物

长期高脂饮食诱导的肥胖小鼠肝脏免疫相关基因的mRNA变化

细胞与分子免疫学杂志

2019

RNA-seq

395

病原体

微生物

Diagnosis of osteoarticular tuberculosis via metagenomic next?generation sequencing: A case report

Experimental and Therapeutic Medicine

1.41

2019

Pathogen detection

396

海葵

动物

Combined transcriptomic and proteomic analysis reveals a diversity of venom-related and toxin-like peptides expressed in the mat anemone Zoanthus natalensis (Cnidaria, Hexacorallia)

Archives of Toxicology

5.728

2019

RNA-seq

397

免疫细胞

Transcriptome Dynamics Reveals Progressive Transition from Effector to Memory in CD4+ T cells

bioRxiv

2019

scRNA-Seq

398

动物

Integrative Analyses of mRNA Expression Profile Reveal the Involvement of IGF2BP1 in Chicken Adipogenesis

International Journal of Molecular Sciences

4.183

2019

RNA-seq

399

Muscle-strain injury exudate favors acute tissue healing and prolonged connective tissue formation in humans

FASEB JOURNAL

5.391

2019

RNA-seq

400

苜蓿

植物

MtBZR1 Plays an Important Role in Nodule Development in Medicago truncatula

International Journal of Molecular Sciences

4.183

2019

RNA-seq

401

肺癌

Lung adenocarcinoma-intrinsic GBE1 signaling inhibits anti-tumor immunity

BMC Genomics

3.501

2019

RNA-seq

402

动物

Comprehensive transcriptomic view of the role of the LGALS12 gene in porcine subcutaneous and intramuscular adipocytes

Molecular Cancer

10.679

2019

RNA-seq

403

Delta-like ligand 4/DLL4 regulates the capillarization of liver sinusoidal endothelial cell and liver fibrogenesis

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

4.739

2019

RNA-seq

404

茶多酚

植物

Pathogenic Effects and Potential Regulatory Mechanisms of Tea Polyphenols on Obesity

BioMed Research International

2.197

2019

Small RNA

405

肉瘤

Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma

BMC Cancer

2.933

2019

WES

406

肝脏

Hepatocyte TRAF6 Aggravates Hepatic Inflammation and Fibrosis by Promoting Lys6 Linked Polyubiquitination of ASK1

hepatology

14.971

2019

RNA-seq

407

Clinical diagnosis of single-gene disorders and chromosomal abnormalities based on BGISEQ-500 platform

bioRxiv

2019

capture

408

宏基因组

微生物

Shotgun Metagenomics of 361 elderly women reveals gut microbiome change in bone mass loss

bioRxiv

2019

metagenome

409

Mixed-lineage leukemia protein 2 suppresses ciliary assembly by the modulation of actin dynamics and vesicle transport

Cell Discovery

4.6

2019

RNA-seq

410

人细胞系

Systematic comparison of germline variant calling pipelines cross multiple next-generation sequencers

Scientific Reports

4.011

2019

WGS&WES

411

诺如病毒

微生物

Replication and transcriptionomic analysis of human noroviruses in human intestinal enteroids

American Journal of Translational Research

3.266

2019

RNA-seq

412

动物

内质网应激标记基因Grp78参与鹅肥肝免疫/炎症状态的调控

畜牧兽医学报

2019

RNA-seq

413

宏基因组

微生物

Alterations in the human gut microbiome associated with Helicobacter pylori infection

FEBS open bio

1.959

2019

metagenome

414

Expanding the Clinical Spectrum of Osteogenesis Imperfecta Type V: 13 Additional Patients and Review

Frontiers in Endocrinology

3.634

2019

WES

415

植物

Integrated transcriptomic and phytochemical analyses provide insights into characteristic metabolites variation in leaves of 1-year-old grafted tea (Camellia sinensis)

Tree Genetics & Genomes

1.862

2019

RNA-seq

416

白细胞

Assessment of the gene expression profiles of leukocytes from different isolations

bioRxiv

2019

RNA-seq

417

肾细胞瘤

Fumaratehydratase-deficient renal cell carcinoma: a clinicopathological and molecular study of 13 cases

Journal of Clinical Pathology

2.346

2019

WGS

418

黄斑病

微生物

Identification and Characterization of a Novel Emaravirus Associated With Jujube (Ziziphus jujuba Mill.) Yellow Mottle Disease

Frontiers in Microbiology

4.259

2019

Small RNA

419

神经母细胞瘤

Exosomal hsa-miR199a-3p Promotes Proliferation and Migration in Neuroblastoma

Frontiers in oncology

4.137

2019

Small RNA

420

乳腺癌

CD137 promotes bone metastasis of breast cancer by enhancing the migration and osteoclast differentiation of monocytes/macrophages

Theranostics

8.063

2019

RNA-seq

421

人细胞系

Fas signaling-mediated TH9 cell differentiation favors bowel inflammation and antitumor functions

Nature Communications

11.878

2019

RNA-seq

422

拟南芥

植物

RAP2.4c and RAP2.4d in the regulation of cold stress and cold priming in Arabidopsis thaliana

REPOSITORIUM DER FREIEN UNIVERSIT?T BERLINGermany

2019

RNA-seq

423

慢性淋巴细胞白血病

Elevated FANCA expression determines a worse prognosis in chronic lymphocytic leukemia and interferes with p53 function

FASEB JOURNAL

5.391

2019

RNA-seq

424

黑色素瘤

The Long Noncoding RNA UCA1 Negatively Regulates Melanogenesis in Melanocytes

Journal of Investigative Dermatology

6.29

2019

lncRNA

425

植物

Enhanced ROS scavenging and sugar accumulation contribute to drought tolerance of naturally occurring autotetraploids in Poncirus trifoliata

PLANT BIOTECHNOLOGY JOURNAL

6.84

2018

RNA-seq

426

古生物

动物

Improving Species Identification of Ancient Mammals Based on Next-Generation Sequencing Data

genes

3.331

2019

WGS

427

宏基因组

微生物

Compositional and functional features of the female premenopausal and postmenopausal gut microbiota

FEBS LETTERS

2.675

2019

metagenome

428

病原体

微生物

Genome-wide Transcript Structure Resolution Reveals Abundant Alternate Isoform Usage from Murine Gammaherpesvirus 68

cell reports

7.815

2019

RNA-seq

429

遗传性脑动脉

Novel and Recurring NOTCH3 Mutations in Two Chinese Patients with CADASIL

Neurodegenerative Diseases

2.798

2019

WES

430

宏基因组

微生物

A survey of the sperm whale (Physeter catodon) commensal microbiome

PeerJ

2.353