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基于华大智造测序平台已发表的文章

2018-12-03

序号

物种

物种大类

文献名称

期刊

影响因子

发表时间

产品

1

叶甲

动物

Comparative transcriptome analysis of chemosensory genes in two sister leaf beetles provides insights into chemosensory speciation.

Insect Biochemistry and Molecular Biology

3.756

2016-11

RNA-Seq

2

cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs

Clinical Epigenetics

4.987

2016-11

Small RNA

3

Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype

Oncotarget

5.168

2017-01

RNA-Seq

4

Overexpression of placenta specific 8 is associated with malignant progression and poor prognosis of clear cell renal cell carcinoma

International Urology and Nephrology

1.564

2017-03

RNA-Seq

5

水稻

植物

Overexpression of OsHSP18.0-CI Enhances Resistance to Bacterial Leaf Streak in Rice

Rice

3.739

2017-04

RNA-Seq

6

克雷伯氏菌

细菌

Coordination of metabolic pathways: Enhanced carbon conservation in 1,3-propanediol production by coupling with optically pure lactate biosynthesis

Metabolic Engineering

8.142

2017-04

RNA-Seq

7

 A reference human genome dataset of the BGISEQ-500 sequencer

GigaScience

6.871

2017-04

WGS

8

大花红景天

植物

Draft genome sequence of the Tibetan medicinal herb, Rhodiola crenulata

GigaScience

6.871

2017-05

RNA-Seq

9

果蝇

动物

Drug induces depression-like phenotypes and alters gene expression profiles in Drosophila

Brain Research Bulletin

3.033

2017-06

RNA-Seq

10

狗和狼

动物

Comparative performance of the BGISEQ-500 versus Illumina HiSeq2500 sequencing platforms for palaeogenomic sequencing

GigaScience

6.871

2017-06

WGS

11

小鼠

动物

Effects of In Utero PFOS Exposure on Transcriptome, Lipidome and Function of Mouse Testis

Environmental Science & Technology

6.198

2017-06

RNA-Seq

12

Recessive mutation in EXOSC3 associates with mitochondrial dysfunction and pontocerebellar hypoplasia

Mitochondrion

3.704

2017-07

RNA-Seq

13

油菜

植物

Genome-scale mRNA transcriptomic insights into the responses of oilseed rape (Brassica napus L.) to varying boron availabilities

Plant and Soil

3.052

2017-07

RNA-Seq

14

小鼠

动物

Nuclear carbonic anhydrase 6B associates with PRMT5 to epigenetically promote IL-12 expression in innate response

PNAS

9.661

2017-07

RNA-Seq&ChIP-Seq

15

Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity

Cell

30.41

2017-07

RNA-Seq

16

Validation of combinatorial probeanchor ligation-based sequencing as non-invasive prenatal test for trisomy at a central laboratory

Ultrasound in Obstetrics & Gynecology

4.71

2017-07

NIFTY

17

拟南芥

植物

AtACS8 plays a critical role in the early biosynthesis of ethylene elicited by copper ions in Arabidopsis

Journal of Cell Science

4.431

2017-08

RNA-Seq

18

The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer.

The Journal of Clinical Investigation

12.784

2017-08

ChIP-Seq

19

文昌鱼

动物

Transcriptome-wide analysis of immune-responsive microRNAs against poly (I:C) challenge in Branchiostoma belcheri by deep sequencing and bioinformatics

Oncotarget

5.168

2017-08

Small RNA

20

PBRM1 restricts the basal activity of innate immune system through repressing RIG-I-like receptor signaling and is a potential prognostic biomarker for colon cancer 

The Journal of  Pathology

6.894

2017-09

RNA-Seq

21

文昌鱼

动物

Exploring gene expression changes in the amphioxus gill after poly(I:C) challenge using digital expression profiling

Fish & Shellfish Immunology

3.148

2017-09

RNA-Seq

22

海参

动物

Genome-wide analysis of gene expression profile in the respiratory tree of sea cucumber (Apostichopus japonicus) in response to hypoxia conditions

Journal of the Marine Biological Association of the United Kingdom

1.038

2017-09

RNA-Seq

23

FH535 Inhibits Proliferation and Motility of Colon Cancer Cells by Targeting Wnt/β-catenin Signaling Pathway

Journal of Cancer

2.916

2017-09

RNA-Seq

24

小鼠

动物

Data Descriptor: RNA sequencing analysis of activated macrophages
treated with the anti-HIV ABX464
in intestinal inflammation

Scientific Data

4.836

2017-10

RNA-Seq

25

小鼠

动物

Orally Administrated Bakers Yeast beta-Glucan Promotes Glucose and Lipid Homeostasis in the Livers of ob/ob Mice

Journal of Agricultural and Food Chemistry

3.154

2017-10

RNA-Seq

26

韭菜迟眼蕈蚊

动物

Using Next-Generation Sequencing to
Detect Differential Expression Genes in Bradysia odoriphaga after Exposure to Insecticides

International Journal of Molecular Sciences

3.226

2017-11

RNA-Seq

27

鹿角杯形珊瑚

动物

Systemic response of the stony coral Pocillopora damicornis against acute cadmium stress

Aquatic Toxicology

4.129

2017-11

RNA-Seq

28

小鼠

动物

Characteristics of NK cells from leukemic microenvironment in MLL-AF9 induced acute myeloid leukemia

Molecular Immunology

3.236

2017-11

RNA-Seq

29

海参

动物

Differential gene expression in the intestine of sea cucumber
(Apostichopus japonicus) under low and high salinity conditions

Comparative Biochemistry and Physiology D-Genomics & Proteomics

2.857

2017-11

RNA-Seq

30

人细胞系

Dual inhibition of DNMTs and EZH2 can overcome both intrinsic and acquired resistance of myeloma cells to IMiDs in a cereblonindependent manner

Molecular oncology

5.314

2017-11

RNA-seq

31

人白血病

Heterogeneous effects of M-CSF isoforms on the progression of MLL-AF9 leukemia

Immunology and cell biology

4.557

2017-11

RNA-seq

32

黄野螟

动物

De novo assembly and identification of antennal transcriptome reveals an olfactory system in Heortia vitessoides (Lepidoptera: Crambidae)

PeerJ

2.17

2017-11

转录组de novo

33

青鳉鱼

动物

Transcriptomic analysis reveals transgenerational effect of hypoxia on the
neural control of testicular functions

Aquatic Toxicology

4.129

2017-12

RNA-Seq

34

苎麻

植物

Gene expression profiling of ramie roots during hydroponic
induction and adaption to aquatic environment

Genomics Data

2.801

2017-12

RNA-Seq

35

Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells

 Journal of Experimental & Clinical Cancer Research

5.189

2017-12

RNA-Seq

36

扩展青霉

真菌

Identification of differentially expressed genes involved in
spore germination of Penicillium expansum by comparative
transcriptome and proteome approaches

MicrobiologyOpen

2.747

2017-12

RNA-Seq

37

胰管腺癌

High expression of diffuse panbronchiolitis critical region 1 gene
promotes cell proliferation, migration and invasion in pancreatic
ductal adenocarcinoma

Biochemical and Biophysical Research Communications

2.466

2017-12

RNA-Seq

38

Probing impaired neurogenesis in human brain organoids exposed to alcohol

Integrative Biology

3.252

2017-12

RNA-Seq

39

Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing

GigaScience

6.871

2017-12

metagenome

40

盐生草

植物

Transcriptome sequencing and comparative analysis of differentially-expressed isoforms in the roots of Halogeton glomeratus under salt stress

Gene

2.415

2017-12

RNA-Seq

41

Isolation and whole genome sequencing of fetal cells from maternal blood towards the ultimate noninvasive prenatal testing

PRENATAL DIAGNOSIS

2.523

2017-12

PGS

42

人细胞系

The epigenetic modifer PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer

Journal of Pathology

6.253

2018-01

RNA-Seq

43

High expression of diffuse panbronchiolitis critical region 1 gene promotes cell proliferation, migration and invasion in pancreatic ductal adenocarcinoma

Biochemical and Biophysical Research Communications

2.466

2018-01

RNA-Seq

44

植物

10KP: A Phylodiverse Genome Sequencing Plan

GigaScience.

7.267

2018-02

推广

45

Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through
repression of phosphoglycerate dehydrogenase

Theranostics

8.766

2018-02

RNA-Seq

46

Advanced Whole-Genome Sequencing and Analysis of Fetal Genomes from Amniotic Fluid

Clinical Chemistry.

8.636

2018-04

PGS

47

番茄

植物

Comparative Transcriptome Profiling of Two Tomato Genotypes in Response to Potassium-Deficiency Stress

International Journal of Molecular Sciences.

3.687

2018-08

RNA-Seq

48

Germline and somatic variant identification using BGISEQ-500 and HiSeq X Ten whole genome sequencing

PLOS ONE

3.057

2018-1

WGS

49

螺和牡蛎

动物

Conserved and ubiquitous expression of  piRNAs and PIWI genes in mollusks antedates the origin of somatic PIWI/piRNA expression to the root of bilaterians

bioRxiv

NA

2018-1

Small RNA

50

拟南芥

植物

Phytochrome A Negatively Regulates the Shade Avoidance Response by Increasing Auxin/Indole Acidic Acid Protein Stability

Developmental Cell

9.174

2018-1

RNA-Seq

51

西瓜

植物

Comparative transcriptome analysis reveals key genes potentially related to soluble sugar and organic acid accumulation in watermelon

PLOS ONE

3.057

2018-1

RNA-Seq

52

青蒿

植物

A novel HD-ZIP IV/MIXTA complex promotes glandular trichome initiation and cuticle development in Artemisia annua

New Phytologist

7.33

2018-1

RNA-Seq

53

A novel mutation in PRPF31, causative of autosomal dominant retinitis pigmentosa, using the BGISEQ-500 sequencer

International journal of ophthalmology

1.1

2018-1

WES

54

大鼠

动物

Preinduction with bone morphogenetic protein-2 enhances cardiomyogenic differentiation of c-kit+ mesenchymal stem cells and repair of infarcted myocardium

International Journal of Cardiology

6.189

2018-1

RNA-seq

55

拟南芥

植物

The GARP/MYB-related grape transcription factor AQUILO improves cold tolerance and promotes the accumulation of raffinose family oligosaccharides

Journal of Experimental Botany

5.83

2018-1

RNA-seq

56

动物

An integrated biomanufacturing platform for the large-scale expansion and neuronal
differentiation of human pluripotent stem cell-derived neural progenitor
cells

Acta Biomaterialia

6.319

2018-1

RNA-seq

57

小鼠

动物

Cambogin suppresses dextran sulphate sodiuminduced colitis by enhancing Treg cell stability and function

British journal of pharmacology

5.49

2018-1

RNA-seq

58

人细胞系

FBXL10 contributes to the development of diffuse large B-cell lymphoma by epigenetically enhancing ERK1/2 signaling pathway

Cell death & disease

5.965

2018-1

RNA-seq

59

拟南芥

植物

Arabidopsis thaliana ACS8 plays a crucial role in the early biosynthesis of ethylene elicited by Cu2+ ions

JOURNAL OF CELL SCIENCE

4.431

2018-1

RNA-seq

60

The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer.

J Pathol

6.253

2018-1

RNA-seq

61

牡蛎

动物

Analysis of in situ Transcriptomes Reveals Divergent Adaptive Response to Hyper- and Hypo-Salinity in the Hong Kong Oyster, Crassostrea hongkongensis

Front. Physiol

3.394

2018-10

RNA-Seq

62

The metagenome of the female upper reproductive tract

Gigascience

7.267

2018-10

宏基因组

63

苜蓿

植物

Multiple Regulatory Networks Are Activated during Cold Stress in Medicago sativa L.

Int J Mol Sci.

3.687

2018-10

RNA de novo

64

细胞系

Multiplex Cell-Free DNA Reference Materials for Quality Control of Next-Generation Sequencing-Based In Vitro Diagnostic Tests of Colorectal Cancer Tolerance.

J Cancer

3.249

2018-10

目标区域捕获

65

细胞系

A new massively parallel nanoball sequencing platform for whole exome research

bioRxiv

NA

2018-10

WES

66

The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function

PLOS ONE

3.057

2018-10

Small RNA

67

生殖道微生物

微生物

The metagenome of the female upper reproductive tract.

Gigascience.

7.267

2018-10

metagenome

68

小鼠

动物

Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in mice

Carbohydrate Polymers

5.158

2018-11

RNA-Seq

69

黄野螟

动物

Candidate olfactory genes identified in Heortia vitessoides(Lepidoptera: Crambidae) by antennal transcriptome analysis

Comparative Biochemistry and Physiology Part D: Genomics and Proteomics

2.913

2018-11

转录组de novo

70

老鼠胚胎
干细胞和人类K562细胞

动物

Comparative analysis of sequencing technologies platforms for single-cell transcriptomics

bioRxiv

NA

2018-11

单细胞RNA-Seq

71

泰国斗鱼

动物

Chromosome-level reference genome of the Siamese fighting fish Betta splendens, a model species for the study of aggression.

Gigascience

7.267

2018-11

动植物基因组

72

技术类

3 Branch ligation: a novelmethod to ligate
non-complementary DNA to recessed or
internal 30OH ends in DNA or RNA

DNA RES

5.404

2018-11

方法学-stLFR接头连接

73

花生

植物

Comparative transcriptome analysis revealed key factors for differential cadmium transport and retention in roots of two contrasting peanut cultivars

BMC genomics

3.73

2018-12

RNAref

74

The application of NIPT using combinatorial probe-anchor synthesis to identify sex chromosomal aneuploidies (SCAs) in a cohort of 570 pregnancies.

Mol Cytogenet

1.167

2018-12

NIPT

75

盐生草

植物

Comparative transcriptome analysis of genes involved in Na+ transport in the leaves of halophyte Halogeton glomeratus

Gene

2.498

2018-12

转录组

76

紫花苜蓿

植物

Comparative Transcriptomic and Physiological Analyses of Medicago sativa L. Indicates that Multiple Regulatory Networks Are Activated during Continuous ABA Treatment.

Int J Mol Sci.

3.687

2018-12

转录组

77

大鼠

动物

Hippocampal gene expression profiling in a rat model of functional constipation reveals abnormal expression genes associated with cognitive function

Neuroscience Letters

2.18

2018-12

RNA-Seq

78

动物

Exosomes derived from preadipocytes improve osteogenic differentiation, potentially via reduced miR?223 expression.

Mol Med Rep.

1.922

2018-12

Small RNA

79

小鼠

动物

Dual extra-retinal origins of microglia in the model of retinal microglia repopulation

Cell Discovery

4.462

2018-2

RNA-Seq

80

Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas throughrepression of phosphoglycerate dehydrogenase

Theranostics

8.766

2018-2

RNA-Seq

81

豌豆蚜

动物

A small set of differentially expressed genes was associated with two color morphs in natural populations of the pea aphid Acyrthosiphon pisum

Gene

2.415

2018-2

RNA-Seq

82

Selenite and methylseleninic acid epigenetically affects distinct gene sets in myeloid leukemia: A
genome wide epigenetic analysis

Free Radical Biology and Medicine

5.606

2018-2

RNA-Seq

83

小鼠

动物

Repopulated microglia are solely derived from the proliferation of residual microglia after
acute depletion

Nature Neuroscience

17.839

2018-2

RNA-Seq

84

Meta

Meta

A novel affordable reagent for room temperature storage and transport of fecal samples for metagenomic analyses

Microbiome

8.496

2018-2

metagenome

85

番茄

植物

Transcriptome resequencing analysis of the responses of Ty5-Mediated resistance to TYLCV via in resistant vs. susceptible tomato cultivars

PeerJ

2.17

2018-2

转录组重测序

86

Efficacy and safety of faecal microbiota transplantation in patients with psoriatic arthritis: protocol for a 6-month, double-blind, randomised, placebo-controlled trial

BMJ OPEN

2.369

2018-2

metagenome

87

人细胞系

Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival

Cell death & disease

5.965

2018-2

RNA-seq

88

小鼠

动物

KRAB-type zinc-finger proteins PITA and PISA specifically regulate p53-dependent glycolysis and mitochondrial respiration

Cell research

15.606

2018-2

RNA-seq

89

小鼠

动物

The LIS1/NDE1 Complex Is Essential for FGF Signaling by Regulating FGF Receptor Intracellular
Trafficking

Cell Reports

8.282

2018-3

RNA-Seq

90

综述类

A guide to sequence your favorite plant genomes

Applications in plant sciences

1.49

2018-3

综述

91

人胃癌

The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1

  Molecular Cancer 

6.204

2018-3

RNA-seq

92

根霉

真菌

Comparative genome-wide analysis of extracellular small RNAs from the mucormycosis pathogen Rhizopus delemar

Scientific Reports

4.259

2018-3

Small RNA

93

甲状腺癌

TBX3 promotes proliferation of papillary thyroid carcinoma cells through facilitating PRC2-mediated p57KIP2 repression

Oncogene

7.519

2018-3

RNA-seq

94

胃癌

Silkworm Pupa Protein Hydrolysate Induces Mitochondria-Dependent Apoptosis and S Phase Cell Cycle Arrest in Human Gastric Cancer SGC-7901 Cells

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

3.226

2018-3

RNA-seq

95

拟南芥

植物

Hydrogen peroxide positively regulates brassinosteroid signaling through oxidation of the BRASSINAZOLE-RESISTANT1 transcription factor

Nature Communications

12.124

2018-3

RNA-seq

96

人细胞系

Small molecules capable of activating DNA methylationrepressed genes targeted by the p38 mitogen-activated protein kinase pathway

Journal of Biological Chemistry

4.125

2018-3

RNA-seq

97

小鼠

动物

PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis

Developmental cell

9.174

2018-3

RNA-seq

98

白血病

Leukemia cell-derived microvesicles induce T cell exhaustion via miRNA delivery

OncoImmunology

7.719

2018-3

RNA-seq

99

酿酒酵母

真菌

RNA-Seq analysis of global transcriptomic changes suggests a roles for the MAPK pathway and carbon metabolism in cell wall maintenance in a Saccharomyces cerevisiae FKS1 mutant

Biochemical and Biophysical Research Communications

2.466

2018-4

转录组重测序

100

卡瓦胡椒

植物

The biosynthetic origin of psychoactive kavalactones in kava

bioRxiv

NA

2018-4

转录组 de novo

101

李斯特菌

细菌

Identification and Characterization of als Genes Involved in D-Allose Metabolism in Lineage II Strain of Listeria monocytogenes

Frontiers in Microbiology

4.076

2018-4

RNA-seq

102

Cupriavidus 贪铜菌

细菌

In Situ Lignin Bioconversion Promotes Complete Carbohydrate Conversion of Rice Straw by Cupriavidus basilensis B-8

ACS Sustainable Chemistry & Engineering

5.95

2018-4

RNA-seq

103

大鼠

动物

Cranial Irradiation Induces Hypothalamic Injury and Late-Onset Metabolic Disturbances in Juvenile Female Rats

DEVELOPMENTAL NEUROSCIENCE

3.03

2018-4

RNA-seq

104

Anti?fbrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohns Disease

Digestive Diseases and Sciences

2.875

2018-4

RNA-seq

105

IVD诊断测试

Quality Control of Next-generation Sequencing-based In vitro Diagnostic Test for Onco-relevant Mutations Using Multiplex Reference Materials in Plasma

Journal of Cancer

2.916

2018-4

综述

106

银屑病

An Interleukin-25-Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin
Inflammation

Immunity

22.845

2018-4

RNA-seq

107

人细胞系

Roles of the CSE1L-mediated nuclear import pathway in epigenetic silencing

PNAS

9.661

2018-4

RNA-seq

108

小麦根际菌

细菌

The Catabolite Repressor/Activator Cra Is a Bridge Connecting Carbon Metabolism and Host Colonization in the Plant Drought Resistance-Promoting Bacterium Pantoea alhagi LTYR-11Z

Applied and Environmental Microbiology

3.807

2018-4

RNA-seq

109

技术类

Single tube bead-based DNA co-barcoding for cost effective and accurate sequencing, haplotyping, and assembly

bioRxiv

NA

2018-5

方法学-大片段

110

玉米象虫

动物

Transcriptome profiling reveals differential gene expression of detoxification enzymes in Sitophilus zeamais responding to terpinen-4-ol fumigation

2.59

2018-5

转录组 de novo

111

Identification of a mutL?homolog 1 mutation via whole?exome sequencing in a Chinese family with Gardner syndrome

Molecular  Medicine Reports

1.692

2018-5

WES

112

大肠杆菌

细菌

Differential gene expression in Escherichia coli during aerosolization from liquid suspension

Applied Microbiology and Biotechnology

3.42

2018-5

RNA-seq

113

大鼠肠道

动物

A gene catalogue of the Sprague-Dawley rat gut metagenome

GigaScience

6.871

2018-5

metagenome

114

龙血树

植物

Complete plastome sequence of Dracaena cambodiana (Asparagaceae): a species considered Vulnerable in Southeast Asia

Mitochondrial DNA Part B

0.488

2018-5

质体DNA

115

人外泌体

Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy

The American Journal of Human Genetics

9.025

2018-5

RNA-seq

116

牡蛎

动物

The Molecular Mechanism Underlying Pro-apoptotic Role of Hemocytes Specific Transcriptional Factor Lhx9 in Crassostrea hongkongensis

Frontiers in Physiology

4.134

2018-5

RNA-seq

117

拟南芥

植物

Overexpression of VaWRKY14 increases drought tolerance in Arabidopsis by modulating the expression of stress-related genes

Plant Cell Reports

2.869

2018-5

RNA-seq

118

盐芥

植物

Compositional and transcriptomic analysis associated with cuticle lipid production on rosette and inflorescence stem leaves in the extremophyte Thellungiella salsuginea

  physiologia plantarum 

3.3

2018-5

RNA-seq

119

酵母

真菌

Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods

Nature Communications

12.124

2018-5

酵母DNA

120

小鼠

动物

Global expression profiling and pathway analysis of mouse mammary tumor reveals strain and stage specific dysregulated pathways in breast cancer progression

Cell Cycle

3.53

2018-5

RNA-seq

121

STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection

Nature Communications

12.124

2018-5

RNA-seq

122

水稻

植物

DDM1 represses noncoding RNA expression and RNA-directed DNA methylation in heterochromatin

Plant Physiology

6.456

2018-5

Small RNA

123

恒河猴

动物

Genetic screening and multipotency in rhesus monkey haploid neural progenitor cells

Development

5.843

2018-5

RNA-seq

124

人唇裂

A novel PTCH1 mutation underlies nonsyndromic cleft lip and/or palate in a Han Chinese family

Oral diseases

2.01

2018-6

WES

125

白背飞虱

动物

Comparative transcriptome analysis of Sogatella furcifera (Horváth) exposed to different insecticides

Scientific Reports

4.259

2018-6

转录组 de novo

126

感染性心内膜炎

Identification of pathogens in culture-negative infective endocarditis with metagenomic analysis

bioRxiv

NA

2018-6

metagenome

127

技术类

Reliable Multiplex Sequencing with Rare Index Mis-Assignment on DNB-Based NGS Platform

bioRxiv

NA

2018-6

方法学-index

128

人细胞

Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy

Journal of Pharmacology and Experimental Therapeutics

3.867

2018-6

RNA-seq&miRNA

129

脐带血细胞

Single-cell Transcriptomic Landscape of Nucleated Cells in
Umbilical Cord Blood

bioRxiv

 NA

2018-6

10X scRNA-seq

130

半滑舌鳎

动物

Transcriptome profiling of immune-responsive genes in the intestine of Cynoglossus semilaevis Günther challenged with Shewanella algae

Fish & Shellfish Immunology

3.148

2018-6

RNA-seq

131

番茄

植物

Expression of grape ACS1 in tomato decreases ethylene and alters the balance between auxin and ethylene during shoot and root formation

Journal of Plant Physiology

3.121

2018-6

RNA-seq

132

分枝杆菌

细菌

Diagnosis of local hepatic tuberculosis through next-generation sequencing: Smarter, faster and better

Clinics and Research in Hepatology and Gastroenterology

2.623

2018-6

133

人细胞

Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth

Nature Communications

12.124

2018-6

RNA-Seq

134

寄生蜂

动物

Parasitic insect-derived miRNAs modulate host development

Nature Communications

12.124

2018-6

Small RNA

135

自发性早产

Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth

PLOS.Genetics

5.54

2018-7

WES

136

小鼠

动物

Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis

Annals of the rheumatic diseases

12.35

2018-7

RNA-Seq

137

动物

RNA-Seq analysis of duck embryo fibroblast cell gene expression during the early stage of egg drop syndrome virus infection

Poultry Science

2.216

2018-7

RNA-Seq

138

黄瓜

植物

Differential Gene Expression Caused by the F and M Loci Provides Insight Into Ethylene-Mediated Female Flower Differentiation in Cucumber

Front. Plant Sci.

3.678

2018-8

RNAref

139

人间质细胞

Differential and Interactive Effects of Substrate Topography and Chemistry on Human Mesenchymal Stem Cell Gene Expression

International Journal of Molecular Sciences.

3.687

2018-8

RNA-Seq

140

拟南芥

植物

Comparative performance of the BGISEQ-500 and Illumina HiSeq4000 sequencing platforms for transcriptome analysis in plants

Plant Methods

4.269

2018-8

转录组

141

水稻

植物

Modulating plant growthmetabolism coordination for sustainable agriculture

Nature

41.577

2018-8

RNA-Seq&ChIP-Seq

142

番茄

植物

Comparative Transcriptome Profiling of Two Tomato Genotypes in Response to Potassium-Deficiency Stress.

International Journal of Molecular Sciences.

3.687

2018-8

RNA-Seq

143

紫甘蓝、芥蓝

植物

Maintenance of grafting-induced epigenetic variations in the asexual progeny of Brassica oleracea and B. juncea chimera

Plant J

5.97

2018-8

Small RNA

144

大麦

植物

Transcriptomic comparison of two barley genotypes differing in arsenic tolerance exposed to arsenate and phosphate treatments

Plant Physiology and Biochemistry

2.718

2018-9

转录组

145

猪肺泡巨噬细胞

动物

Transcriptome of porcine alveolar macrophages activated by interferon-gamma and lipopolysaccharide

Biochemical and Biophysical Research Communications

2.559

2018-9

RNA-Seq

146

斑马鱼

动物

Transcriptome analysis reveals functional roles of nacreous protein N16 in prednisolone-induced osteoporotic zebrafish

International Journal of Biological Macromolecules

3.909

2018-9

RNA-Seq

147

小鼠

动物

Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation

Neuron

14.318

2018-9

RNA-Seq

148

植物

Combination of iTRAQ proteomics and RNA-seq transcriptomics reveals jasmonate-related-metabolisms central regulation during the process of Jujube witches broom recovery by tetracycline treatment

Scientia Horticulturae

1.76

2019-01

转录组

149

苦皮藤

植物

De novo leaf and root transcriptome analysis to explore biosynthetic pathway of Celangulin V in Celastrus angulatus maxim

BMC genomics

3.73

2019-01

转录组

150

烟草

植物

Tolerance of Transplastomic Tobacco Plants Overexpressing a Theta Class Glutathione Transferase to Abiotic and Oxidative Stresses

Front. Plant Sci

3.678

2019-01

转录组

151

单纯疱疹病毒

病毒

Identification of Putative UL54 (ICP27) Transcription Regulatory Sequences Binding to Oct-1, v-Myb, Pax-6 and Hairy in Herpes Simplex Viruses

Journal of Cancer

3.249

2019-01

小基因组

152

十字花科

植物

The complete plastid genomes of four species from Brassicales

Mitochondrial DNA Part B

0.488

2019-01

小基因组

153

赖氏菌

细菌

Functional analysis of Leifsonia xyli subsp. xyli membrane protein gene Lxx18460 (anti-sigma K)

BMC Microbiology

2.829

2019-01

转录组de novo

154

文昌鱼

动物

Genome-wide gene expression analysis reveals novel insights into the response to nitrite stress in gills of Branchiostoma belcheri

Chemosphere

4.427

2019-01

RNA-seq

155

宏基因组

微生物

Exploring the human microbiome: The potential future role of next-generation sequencing in disease diagnosis and treatment

Frontiers in Immunology

5.511

2019-01

综述

156

文昌鱼

动物

Genome-wide transcriptional response of microRNAs to the benzo(a)pyrene stress in amphioxus Branchiostoma belcheri

Chemosphere

4.427

2019-01

miRNA-seq

157

斑马鱼

动物

Microcystin-LR exposure induced nephrotoxicity by triggering apoptosis in female zebrafish

Chemosphere

4.427

2019-01

RNAref

158

鳞状细胞肺癌

Genomic sequencing and editing revealed the GRM8 signaling pathway as potential therapeutic targets of squamous cell lung cancer

Cancer letters

6.491

2019-01

WGS

159

鼻咽癌

FOXA1 reprograms the TGF-β-stimulated transcriptional program from a metastasis promoter to a tumor suppressor in nasopharyngeal carcinoma

Cancer letters

6.491

2019-01

RNA-seq

160

番茄

植物

Overexpression of the KNOX gene Tkn4 affects pollen development and confers sensitivity to gibberellin and auxin in tomato

Plant Science

3.712

2019-01

RNA-seq

161

番茄

植物

A tomato Bbox protein SlBBX20 modulates carotenoid biosynthesis by directly activating PHYTOENE SYNTHASE 1, and is targeted for 26S proteasomemediated degradation

New Phytologist

7.433

2019-01

RNA-seq

162

胚胎肾细胞

Knockdown of KDM2A inhibits proliferation associated with TGF-β expression in HEK293T cell

Molecular and Cellular Biochemistry

2.561

2019-01

RNA-seq

163

鼠前体脂肪细胞

动物

Exosomes derived from preadipocytes improve osteogenic differentiation, potentially via reduced miR?223 expression

Molecular Medicine Reports

1.922

2019-01

RNA-seq

164

膀胱癌细胞系

CINP is a novel cofactor of KLF5 required for its role in the promotion of cell proliferation, survival and tumor growth

International journal of cancer

7.36

2019-01

RNA-seq

165

技术类

Arthropod Genome Sequencing and Assembly Strategies

Insect Genomics

NA

2019-01

综述

166

秀丽隐杆线虫

动物

A Persistence Detector for Metabolic Network Rewiring in an Animal

Cell Reports

8.032

2019-01

RNA-seq

167

芥菜

植物

Chromosome level comparative analysis of Brassica genomes

Plant Molecular Biology

3.543

2019-01

基因组Hi-C

168

水稻

植物

The basic helixloophelix transcription factor, OsPIL15 regulates grain size via directly targeting a purine permease gene OsPUP7 in rice

Plant Biotechnology Journal

6.305

2019-01

RNA-seq

169

肺炎杆菌

细菌

MALDI-TOF Characterization of Protein Expression Mutation During Morphological Changes of Bacteria Under the Impact of Antibiotics

Anal. Chem

6.042

2019-01

RNA-seq

170

Hela细胞

Genome-wide identification of protein binding sites on RNAs in mammalian cells

Biochemical and Biophysical Research Communications

2.559

2019-01

RNA-seq

171

乳腺癌和卵巢癌

Frequency of mutations in 21 hereditary breast and ovarian cancer susceptibility genes among high-risk Chinese individuals

bioRxiv

NA

2019-01

WGS

172

肠道微生物

Nonobese subjects of Bacteroides and Prevotella enterotype 2 responded differentially to calorie restriction intervention

bioRxiv

NA

2019-01

宏基因组

173

IVD诊断测试

综述

High-throughput sequencing for the aetiologic identification of viral encephalitis, meningoencephalitis and meningitis. A narrative review and clinical appraisal

Clinical Microbiology and Infection

5.394

2019-01

综述

174

病毒

微生物

Genome comparison of African swine fever virus China/2018/AnhuiXCGQ strain and related European p72 Genotype II strains

Transboundary and Emerging Diseases

3.504

2019-01

小基因组

175

多毛纲动物

动物

Complete mitogenome of a Baltic Sea specimen of the non-indigenous polychaete Marenzelleria neglecta

Mitochondrial DNA Part B

0.488

2019-01

小基因组

176

/小鼠

动物

Dean flow assisted single cell and bead encapsulation for high performance single cell expression profiling

bioRxiv

NA

2019-01

scRNA-seq

177

小鼠

动物

Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue

PLoS One

2.766

2019-01

RNA-seq

178

紫花苜蓿

植物

Full-length transcript sequencing and comparative transcriptomic analysis to evaluate the contribution of osmotic and ionic stress components towards salinity tolerance in the roots of cultivated alfalfa (Medicago sativa L.)

BMC genomics

3.73

2019-01

PB RNA de novo

179

An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos

Nature Communication

12.353

2019-01

RNA-seq

180

Human epidermal growth factor receptor 2 amplification as a biomarker for treatment in patients with lymph node?metastatic penoscrotal extramammary Paget's disease

Oncology Letters

1.664

2019-01

DNA

181

新秀丽隐杆线虫

动物

The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans

PLoS genetics

5.54

2019-01

RNA-seq &ChIP-seq

182

Actualités du séquen?age dADN-Chroniques génomiques

Med Sci (Paris)

NA

2019-01

综述

183

The identification of a transthyretin variant p.D38G in a Chinese family with early-onset leptomeningeal amyloidosis

Journal of Neurology

3.783

2019-01

WES

184

Pathogens in Patients with Granulomatous lobular mastitis

International Journal of Infectious Diseases

3.202

2019-01

WGS

185

岩鱼

动物

A chromosome-level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birth

bioRxiv

NA

2019-01

基因组

186

拟南芥

植物

Functional analysis for domains of maize PPR protein EMP5 in RNA editing and plant development in Arabidopsis

Plant Growth Regulation

2.081

2019-01

RNAref

187

Toxoplasma gondii ROP17 inhibits the innate immune response of HEK293T cells to promote its survival

Parasitology Research

2.558

2019-01

RNAref

188

Meta

Clinical metagenomic next-generation sequencing for pathogen detection 

Annual Review of Pathology: Mechanisms of Disease

NA

2019-01

综述

189

小鼠

动物

Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation

International journal of cancer

7.36

2019-01

miRNA

190

人细胞

Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity

Nature Communication

12.353

2019-01

scCAT-seq

191

All Aboard The Genome Exprees: Is a new generation of DNA sequencing technology about to hit the fast track?

Genetic Engineering & Biotechnology New

NA

2019-01

综述

192

印度尼西亚水果

植物

Datasets for genome assembly of six underutilized Indonesian fruits

Data in Brief

NA

2019-01

基因组

193

MicroRNA profiling from dried blood samples

Critical Reviews in Clinical Laboratory Sciences

NA

2019-01

综述

194

水稻

植物

Expression of Maize MADS Transcription Factor ZmES22 Negatively Modulates Starch Accumulation in Rice Endosperm

International journal of molecular sciences

3.687

2019-01

RNA-seq

195

维管植物

植物

Molecular digitization of a botanical garden: high-depth whole genome sequencing of 689 vascular plant species from the Ruili Botanical Garden

GigaScience

7.267

2019-01

基因组

196

Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report

Journal of Bone and Joint Infection

NA

2019-01

宏基因组

197

The vagino-cervical microbiome as a woman's life history

bioRxiv

NA

2019-01

宏基因组

198

秀丽隐杆线虫

动物

Systematic evaluation of C. elegans lincRNAs with CRISPR knockout mutants

Genome Biology

13.214

2019-1

lncRNA

199

迷你水晶鱼骨鱼

动物

Hybrid genome assembly and annotation of Danionella translucida, a transparent fish with the smallest known vertebrate brain

bioRxiv

NA

2019-02

RNA-seq

200

企鹅

动物

Mitogenomes uncover extinct penguin taxa and reveal island formation as a key driver of speciation

Molecular Biology and Evolution

10.217

2019-02

小基因组

201

番茄

植物

SlMYB75, an MYB-type transcription factor, promotes anthocyanin accumulation and enhances volatile aroma production in tomato fruits

Horticulture Research

3.368

2019-02

RNA-seq

202

小鼠

动物

The effects of perfluorooctanoate on high fat diet induced non-alcoholic fatty liver disease in mice

Toxicology

3.265

2019-02

RNA-seq

203

西洋参

植物

Characterization of the complete chloroplast genome of American ginseng, Panax quinquefolius L

Mitochondrial DNA Part B

0.488

2019-02

小基因组

204

楠木

植物

Characterization of the complete chloroplast genome of the Phoebe zhennan S. Lee

Mitochondrial DNA Part B

0.488

2019-02

小基因组

205

抹香鲸

动物

The first chromosomelevel genome for a marine mammal as a resource to study ecology and evolution

Molecular Ecology Resources

7.059

2019-02

基因组

206

卵巢癌病人

The biodiversity Composition of Microbiome in Ovarian Carcinoma Patients

Scientific Reports

4.122

2019-02

RNA-seq

207

苹果

植物

Methylome and transcriptome analyses of apple fruit somatic mutations reveal the difference of red phenotype

BMC Genomics

3.73

2019-02

RNA-seq

208

玉米

植物

Molecular Mechanisms Underlying Increase in Lysine Content of Waxy Maize through the Introgression of the opaque2 Allele

International Journal of Molecular Sciences

3.687

2019-02

RNA-seq

209

茄子

植物

Comparative transcriptome analysis reveals K+ transporter gene contributing to salt tolerance in eggplant

BMC Plant Biology

3.93

2019-02

RNA-seq

210

肾功能损伤病人

A Novel Heterozygous Mutation of the COL4A3 Gene Causes a Peculiar Phenotype without Hematuria and Renal Function Impairment in a Chinese Family

Disease Markers

2.949

2019-02

目标区域

211

人肿瘤细胞

Eradication of glioblastoma by immuno-virotherapy with a retargeted oncolytic HSV in a preclinical model

Oncogene

6.854

2019-02

RNA-seq

212

虫草蛆

动物

Genome-wide analysis of developmental stage-specific transcriptome in Bradysia odoriphaga

Comparative Biochemistry and Physiology Part D: Genomics and Proteomics

2.913

2019-02

RNA-seq

213

人细胞系

Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells

Nucleic Acids Research

11.561

2019-02

RNAref

214

RNA

动物/植物

Ancient RNA from Late Pleistocene permafrost and historical canids shows tissue-specific transcriptome survival

bioRxiv

NA

2019-02

RNAref

215

乳酸菌

细菌

Two strains of Lactobacilli effectively decrease the colonization of VRE in a mouse model

Frontiers in cellular and infection microbiology

3.52

2019-02

RNA-seq

216

大鼠

动物

Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro.

Aging-US

5.179

2019-02

RNA-seq

217

小鼠

动物

Specific Decrease in B-Cell-Derived Extracellular Vesicles Enhances Post-Chemotherapeutic CD8+ T Cell Responses

Immunity

19.734

2019-02

RNA-seq

218

卵巢癌

C/EBPβ enhances platinum resistance of ovarian
cancer cells by reprogramming H3K79 methylation

Nature Communications

12.124

2019-04

WES

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